Gene Symbol | PIP5K1B |
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Entrez Gene | 8395 |
Alt Symbol | MSS4, STM7 |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol-4-phosphate 5-kinase, type I, beta |
Other Description | PIP5K1-beta|PIP5KIbeta|phosphatidylinositol 4-phosphate 5-kinase type I beta|phosphatidylinositol 4-phosphate 5-kinase type-1 beta|phosphatidylinositol-4-phosphate 5-kinase type-1 beta|protein STM-7|ptdIns(4)P-5-kinase 1 beta|type I phosphatidylinositol 4-phosphate 5-kinase beta|type I phosphatidylinositol-4-phosphate 5-kinase beta |
Swissprots | P78519 Q8NHQ5 Q5T5K8 Q92749 O14986 Q7KYT5 Q5T5K6 P78518 B4DIG7 Q5T5K9 Q5VZ00 A8K9L9 |
Accessions | AAC51327 EAW62465 EAW62466 EAW62467 O14986 AK292734 BAF85423 AK295587 BAG58479 BC030587 AAH30587 CB988216 CK299479 DQ890874 ABM81800 DQ894030 ABM84956 U78579 AAC50914 U78580 AAC50915 U78581 AAC50916 XM_005252261 XP_005252318 XM_005252262 XP_005252319 XM_006717300 XP_006717363 XM_006717301 XP_006717364 XM_011519082 XP_011517384 XM_011519083 XP_011517385 XM_011519084 XP_011517386 XM_011519085 XP_011517387 NM_001031687 NM_001278253 NP_001265182 NM_003558 NP_003549 |
Function | Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of PLD2. Together with PIP5K1A is required after stimulation of G-protein coupled receptors for stable platelet adhesion (By similarity). {ECO:0000250}. |
Subcellular Location | Endomembrane system {ECO:0000250}. Note=Associated with membranes. {ECO:0000250}. |
Tissue Specificity | Detected in heart, pancreas, brain, kidney, skeletal muscle and lung. {ECO:0000269|PubMed:8955136}. |
Top Pathways | Fc gamma R-mediated phagocytosis, Endocytosis, Choline metabolism in cancer, Inositol phosphate metabolism, Regulation of actin cytoskeleton |
Active human PIP5K1 beta full length protein - ab125547 from Abcam
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Human PIP5K1 beta full length protein - ab160018 from Abcam
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Human PIP5K1 beta protein fragment - ab160019 from Abcam
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PIP5K1B Antibody Blocking Peptide - LS-E9446 from LifeSpan Bioscience
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PIP5K1B Antibody Blocking Peptide - LS-E24182 from LifeSpan Bioscience
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Recombinant Human MSS4 Protein - H00008395-P01 from Novus Biologicals
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MSS4 Partial Recombinant Protein - H00008395-Q01 from Novus Biologicals
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MSS4 Peptide - P3020 from Novus Biologicals
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PIP5K1B-Antibody-N-term-Blocking-Peptide - BP8038a from Abgent, a WuXi AppTec company
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RABIF blocking peptide - GTX88549-PEP from GeneTex
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RABIF protein (His tag) - 80R-1454 from Fitzgerald
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PIP5K1B - H00008395-P01-10 from Acris Antibodies
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PIP5K1B - H00008395-P01-25 from Acris Antibodies
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PIP5K1B - H00008395-Q01-10 from Acris Antibodies
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PIP5K1B - H00008395-Q01-25 from Acris Antibodies
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PIP5K1B fusion protein - Ag3261 from Proteintech Group
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RABIF Human - PRPS-307 from NeoScientific
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Recombinant Human PIP5K1B, His-tagged - PIP5K1B-1728H from Creative Biomart
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Recombinant Human PIP5K1B (Active), GST-tagged - PIP5K1B-1461H from Creative Biomart
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RABIF 1-123aa - CMB-525 from Reagent Proteins
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RABIF - NKX-7RP from Reagent Proteins
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Recombinant Human Phosphatidylinositol 4-phosphate 5-kinase type-1 beta(PIP5K1B) - CSB-YP018026HU CSB-EP018026HU CSB-BP018026HU CSB-MP018026HU from Cusabio
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PIP5K1B Protein - abx163437 from Abbexa
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PIP5K1B (transcript variant 2) - TP323713 from Acris Antibodies
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Phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1B), Recombinant Protein - MBS1212753 from MyBioSource
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