PIP5K1B

Gene Symbol PIP5K1B
Entrez Gene 8395
Alt Symbol MSS4, STM7
Species Human
Gene Type protein-coding
Description phosphatidylinositol-4-phosphate 5-kinase, type I, beta
Other Description PIP5K1-beta|PIP5KIbeta|phosphatidylinositol 4-phosphate 5-kinase type I beta|phosphatidylinositol 4-phosphate 5-kinase type-1 beta|phosphatidylinositol-4-phosphate 5-kinase type-1 beta|protein STM-7|ptdIns(4)P-5-kinase 1 beta|type I phosphatidylinositol 4-phosphate 5-kinase beta|type I phosphatidylinositol-4-phosphate 5-kinase beta
Swissprots P78519 Q8NHQ5 Q5T5K8 Q92749 O14986 Q7KYT5 Q5T5K6 P78518 B4DIG7 Q5T5K9 Q5VZ00 A8K9L9
Accessions AAC51327 EAW62465 EAW62466 EAW62467 O14986 AK292734 BAF85423 AK295587 BAG58479 BC030587 AAH30587 CB988216 CK299479 DQ890874 ABM81800 DQ894030 ABM84956 U78579 AAC50914 U78580 AAC50915 U78581 AAC50916 XM_005252261 XP_005252318 XM_005252262 XP_005252319 XM_006717300 XP_006717363 XM_006717301 XP_006717364 XM_011519082 XP_011517384 XM_011519083 XP_011517385 XM_011519084 XP_011517386 XM_011519085 XP_011517387 NM_001031687 NM_001278253 NP_001265182 NM_003558 NP_003549
Function Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of PLD2. Together with PIP5K1A is required after stimulation of G-protein coupled receptors for stable platelet adhesion (By similarity). {ECO:0000250}.
Subcellular Location Endomembrane system {ECO:0000250}. Note=Associated with membranes. {ECO:0000250}.
Tissue Specificity Detected in heart, pancreas, brain, kidney, skeletal muscle and lung. {ECO:0000269|PubMed:8955136}.
Top Pathways Fc gamma R-mediated phagocytosis, Endocytosis, Choline metabolism in cancer, Inositol phosphate metabolism, Regulation of actin cytoskeleton

PIPK I β (D-19) - sc-11778 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PIPK I β (D-19): sc-11778. Immunoperoxidase staining of formalin fixed, paraffin-embedded human skeletal muscle tissue showing cytoplasmic staining of myocytes.

PIPK I β (L-17) - sc-11779 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PIPK I β (L-17): sc-11779. Western blot analysis of PIPK I β expression in non-transfected: sc-117752 (A) and human PIPK I β transfected: sc-170198 (B) 293T whole cell lysates.

PIPK I β (N-17) - sc-11777 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PIP5K1 beta antibody - ab5468 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Anti-PIP5K1 beta antibody - ab121309 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab121309 at 1/75 dilution staining PIP5K1 in Paraffin-embedded Human skeletal muscle tissue by Immunohistochemistry.

Anti-PIP5K1 beta antibody [EPR9268] - ab154818 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9268
All lanes : Anti-PIP5K1 beta antibody [EPR9268] (ab154818) at 1/1000 dilutionLane 1 : Human placenta tissue lysateLane 2 : Human fetal kidney tissue lysateLysates/proteins at 10 µg per lane.

Anti-PIP5K1B Antibody (aa395-444) - LS-C169800 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PIP5K1B Antibody (aa1-30) - LS-C101113 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with PIP5K1B antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-PIP5K1B Antibody (N-Terminus, AP) - LS-C280795 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIP5K1B Antibody (N-Terminus, APC) - LS-C280796 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIP5K1B Antibody (N-Terminus, Biotin) - LS-C280800 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIP5K1B Antibody (N-Terminus, FITC) - LS-C280801 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIP5K1B Antibody (N-Terminus, Azide-free, HRP) - LS-C280802 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIP5K1B Antibody (N-Terminus, PE) - LS-C280803 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIP5K1B Antibody (N-Terminus) - LS-C328202 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

MSS4 Antibody - NBP1-87832 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MSS4 Antibody - H00008395-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: MSS4 Antibody [H00008395-A01] - PIP5K1B polyclonal antibody (A01), Lot # 060927JCS1 Western Blot analysis of PIP5K1B expression in Y-79 ( Cat # L042V1 ).

Anti-PIP5K1B (491-505) antibody produced in rabbit - I6660 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-PIP5K1B (491-505) (RB): <B>Cat. No. I6660</B>: Immunofluorescence of HUVEC cells using PIP5K1B (491-505) (RB), <B>Cat. No. I6660</B> (red) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used.<BR/>Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-PIP5K1B (491-505) antibody produced in rabbit - K0767 from Sigma-Aldrich

Prices $342.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-PIP5K1B (491-505) (RB): <B>Cat. No. K0767</B>: Immunofluorescence of HUVEC cells using PIP5K1B (491-505) (RB), <B>Cat. No. K0767</B> (red) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used.<BR/>Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-PIP5K1B antibody produced in rabbit - HPA009687 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PIP5K1B: <B>Cat. No. HPA009687</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human skeletal muscle shows strong cytoplasmic positivity in myocytes.

Anti-PIP5K1B (286-300) antibody produced in rabbit - I6535 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-PIP5K1B (286-300) (RB): <B>Cat. No. I6535</B>: Immunofluorescence of HUVEC cells using PIP5K1B (286-300) (RB), <B>Cat. No. I6535</B> (red) at a 1:100 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used.<BR/>Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

PIP5K1B Antibody - C-terminal region (ARP66635_P050) - ARP66635_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PIP5K1B-Antibody-N-term - AP8038a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of anti-PIP5K1B Pab (Cat. #AP8038a) in human placenta cell lysate. PIP5K1B (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

PIP5K1B Antibody - N-terminal region (OAAB17396) - OAAB17396 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

PIP5K1B antibody - 70R-19301 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
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