PPFIA1

Gene Symbol PPFIA1
Entrez Gene 8500
Alt Symbol LIP.1, LIP1, LIPRIN
Species Human
Gene Type protein-coding
Description protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
Other Description LAR-interacting protein 1|LIP-1|Liprin-alpha1|PTPRF-interacting protein alpha-1|liprin-alpha-1|protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1
Swissprots Q8N4I2 Q14567 A6NLE3 Q13136 Q13135
Accessions EAW74763 EAW74764 EAW74765 Q13136 AB209314 BAD92551 AK123331 BAG53890 AK124621 BAG54059 AW163189 BC034046 AAH34046 BF352121 BX648037 CK902590 D49354 BAA08353 DQ892401 ABM83327 U22815 AAC50172 U22816 AAC50173 XM_006718716 XP_006718779 XM_011545306 XP_011543608 XM_011545307 XP_011543609 XM_011545308 XP_011543610 XM_011545309 XP_011543611 XM_011545310 XP_011543612 XM_011545311 XP_011543613 XM_011545312 XP_011543614 XM_011545313 XP_011543615 XM_011545314 XP_011543616 XM_011545315 XP_011543617 XM_011545316 XP_011543618 XM_011545317 XP_011543619 XM_011545318 XP_011543620 XM_011545319 XP_011543621 NM_003626 NP_003617 NM_177423 NP_803172 NR_045286
Function May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. {ECO:0000269|PubMed:7796809}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:7796809}. Note=Colocalizes with PTPRF at the ends of focal adhesions most proximal to the cell nucleus.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:7796809, ECO:0000269|PubMed:9624153}.

Liprin α1 (A-2) - sc-374477 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Liprin α1 (A-2): sc-374477. Western blot analysis of Liprin α1 expression in MDA-MB-468 (A) and 293T (B) whole cell lysates.

Liprin α1 (A-6) - sc-398030 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Liprin α1 (A-6): sc-398030. Western blot analysis of Liprin α1 expression in BT-20 (A), MDA-MB-468 (B), Jurkat (C), HeLa (D) and MDA-MB-231 (E) whole cell lysates.

Liprin α1 (H-89) - sc-67262 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Liprin α1 (H-89): sc-67262. Western blot analysis of Liprin α1 expression in BT-20 whole cell lysate.

Liprin α1 (A-5) - sc-376141 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Liprin α1 (A-5): sc-376141. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Liprin α1 (G-19) - sc-54037 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Liprin α1 (G-19): sc-54037. Western blot analysis of Liprin α1 expression in BT-20 whole cell lysate.

Liprin α1 (F-1) - sc-271373 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Liprin α1 (F-1): sc-271373. Western blot analysis of Liprin α1 expression in BT-20 whole cell lysate.

Liprin α1 (F-6) - sc-271664 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Liprin α1 (F-6): sc-271664. Western blot analysis of Liprin α1 expression in BT-20 whole cell lysate.

Liprin α1 (K-14) - sc-54038 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Liprin α1 (K-14): sc-54038. Western blot analysis of Liprin α1 expression in HeLa (A), MCF7 (B) and U-251-MG (C) whole cell lysates.

Liprin α1 (S-20) - sc-54039 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Liprin α1 (S-20): sc-54039. Western blot analysis of Liprin α1 expression in BT-20 whole cell lysate.

Liprin α1 (T-20) - sc-54040 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Liprin α1 (T-20): sc-54040. Western blot analysis of Liprin α1 expression in BT-20 (A) and MDA-MB-468 (B) whole cell lysates.

LIP1 (H-300) - sc-134669 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LIP1 (H-300): sc-134669. Western blot analysis of LIP1 expression in Jurkat (A) and NIH/3T3 (B) whole cell lysates.

Anti-Liprin alpha 1 antibody - ab26192 from Abcam

Prices $406.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-Liprin alpha 1 antibody - ab96377 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Liprin alpha 1 antibody (ab96377) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg

Anti-Liprin alpha 1 antibody - N-terminal - ab173205 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Liprin alpha 1 antibody - N-terminal (ab173205) at 1/100 dilution + MDA-MB231 cell line lysates at 35 µg

Anti-PPFIA1 / LIPRIN Antibody (aa18-277) - LS-C186394 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence of methanol-fixed A431 using Liprin alpha 1 antibody at 1:200 dilution.

Anti-PPFIA1 / LIPRIN Antibody (aa52-80, AP) - LS-C266813 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPFIA1 / LIPRIN Antibody (aa52-80, APC) - LS-C266814 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPFIA1 / LIPRIN Antibody (aa52-80, Biotin) - LS-C266815 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPFIA1 / LIPRIN Antibody (aa52-80, FITC) - LS-C266816 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPFIA1 / LIPRIN Antibody (aa52-80, Azide-free, HRP) - LS-C266818 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPFIA1 / LIPRIN Antibody (aa52-80, PE) - LS-C266820 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPFIA1 / LIPRIN Antibody (aa51-80) - LS-C324209 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPFIA1 / LIPRIN Antibody (aa52-80) - LS-C158702 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PPFIA1 Antibody western blot of MDA-MB231 cell line lysates (35 ug/lane). The PPFIA1 antibody detected the PPFIA1 protein (arrow).

Liprin alpha 1 Antibody - NBP2-38494 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Liprin alpha 1 Antibody [NBP2-38494] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & focal adhesion sites.

Liprin alpha 1 Antibody - 21720002 from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Liprin alpha 1 Antibody [21720002] - Samples: Lane 1, Marker [kDa]: 250, 130, 95, 72, 55, 36, 28, 17, 11 Lane 2, RT-4 Lane 3, U-251MG sp Lane 4, Human Plasma Lane 5, Liver Lane 6, Tonsil, Target weight [kDa]: 136, 134 (splice variants) Validation score: 2 Validation description: Supportive - Band of predicted size in kDa (+/-20%) with additional bands present.
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