Gene Symbol | PPFIA1 |
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Entrez Gene | 8500 |
Alt Symbol | LIP.1, LIP1, LIPRIN |
Species | Human |
Gene Type | protein-coding |
Description | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 |
Other Description | LAR-interacting protein 1|LIP-1|Liprin-alpha1|PTPRF-interacting protein alpha-1|liprin-alpha-1|protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1 |
Swissprots | Q8N4I2 Q14567 A6NLE3 Q13136 Q13135 |
Accessions | EAW74763 EAW74764 EAW74765 Q13136 AB209314 BAD92551 AK123331 BAG53890 AK124621 BAG54059 AW163189 BC034046 AAH34046 BF352121 BX648037 CK902590 D49354 BAA08353 DQ892401 ABM83327 U22815 AAC50172 U22816 AAC50173 XM_006718716 XP_006718779 XM_011545306 XP_011543608 XM_011545307 XP_011543609 XM_011545308 XP_011543610 XM_011545309 XP_011543611 XM_011545310 XP_011543612 XM_011545311 XP_011543613 XM_011545312 XP_011543614 XM_011545313 XP_011543615 XM_011545314 XP_011543616 XM_011545315 XP_011543617 XM_011545316 XP_011543618 XM_011545317 XP_011543619 XM_011545318 XP_011543620 XM_011545319 XP_011543621 NM_003626 NP_003617 NM_177423 NP_803172 NR_045286 |
Function | May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. {ECO:0000269|PubMed:7796809}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:7796809}. Note=Colocalizes with PTPRF at the ends of focal adhesions most proximal to the cell nucleus. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:7796809, ECO:0000269|PubMed:9624153}. |
LIAS / LIP1 Antibody Blocking Peptide - LS-E17610 from LifeSpan Bioscience
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LIAS / LIP1 Antibody Blocking Peptide - LS-E17611 from LifeSpan Bioscience
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PPFIA1 / LIPRIN Antibody Blocking Peptide - LS-E5022 from LifeSpan Bioscience
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PPFIA1-Antibody-N-term-Blocking-Peptide - BP17425a from Abgent, a WuXi AppTec company
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PPFIA1 fusion protein - Ag5381 from Proteintech Group
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Recombinant Human PPFIA1, GST-tagged - PPFIA1-1879H from Creative Biomart
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Recombinant Human Liprin-alpha-1(PPFIA1) ,partial - CSB-YP618760HU CSB-EP618760HU CSB-BP618760HU CSB-MP618760HU from Cusabio
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Liprin-alpha-1 (transcript variant 1) - TP312893 from Acris Antibodies
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Recombinant Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1) - RPD614Hu01 from Uscn Life Science Inc.
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Liprin alpha 1 Recombinant Protein Antigen - NBP2-38494PEP from Novus Biologicals
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PPFIA1 Peptide, Human - M34GP12182H from Creative Peptides
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PPFIA1 Recombinant Protein (OPCD00409) - OPCD00409 from Aviva Systems Biology
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Liprin alpha 1 Recombinant Protein Antigen - NBP2-58915PEP from Novus Biologicals
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Liprin-alpha-1 (PPFIA1), partial, Recombinant Protein - MBS1452229 from MyBioSource
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Protein Tyrosine Phosphatase F Interacting Protein 1, Recombinant Protein - MBS2034498 from MyBioSource
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