| Gene Symbol |
PPFIA1
|
| Entrez Gene |
8500
|
| Alt Symbol |
LIP.1, LIP1, LIPRIN
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
|
| Other Description |
LAR-interacting protein 1|LIP-1|Liprin-alpha1|PTPRF-interacting protein alpha-1|liprin-alpha-1|protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1
|
| Swissprots |
Q8N4I2 Q14567 A6NLE3 Q13136 Q13135
|
| Accessions |
EAW74763 EAW74764 EAW74765 Q13136 AB209314 BAD92551 AK123331 BAG53890 AK124621 BAG54059 AW163189 BC034046 AAH34046 BF352121 BX648037 CK902590 D49354 BAA08353 DQ892401 ABM83327 U22815 AAC50172 U22816 AAC50173 XM_006718716 XP_006718779 XM_011545306 XP_011543608 XM_011545307 XP_011543609 XM_011545308 XP_011543610 XM_011545309 XP_011543611 XM_011545310 XP_011543612 XM_011545311 XP_011543613 XM_011545312 XP_011543614 XM_011545313 XP_011543615 XM_011545314 XP_011543616 XM_011545315 XP_011543617 XM_011545316 XP_011543618 XM_011545317 XP_011543619 XM_011545318 XP_011543620 XM_011545319 XP_011543621 NM_003626 NP_003617 NM_177423 NP_803172 NR_045286
|
| Function |
May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. {ECO:0000269|PubMed:7796809}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:7796809}. Note=Colocalizes with PTPRF at the ends of focal adhesions most proximal to the cell nucleus.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:7796809, ECO:0000269|PubMed:9624153}.
|