Gene Symbol | CASP12 |
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Entrez Gene | 100506742 |
Alt Symbol | CASP-12, CASP12P1 |
Species | Human |
Gene Type | protein-coding |
Description | caspase 12 (gene/pseudogene) |
Other Description | caspase 12 pseudogene 1|inactive caspase-12 |
Swissprots | Q6UXS9 D6RBN7 |
Accessions | Q6UXS9 AF464191 AF464192 AF464193 AF464194 AF464195 AF486844 AF486845 AF486846 AF486847 AY358222 AAQ88589 BG183061 NM_001191016 NP_001177945 NR_034061 NR_034063 NR_034064 NR_034065 NR_034066 NR_034067 NR_034068 NR_034070 NR_034071 NR_000035 |
Function | Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF. {ECO:0000269|PubMed:12054529, ECO:0000269|PubMed:15129283}. |
Tissue Specificity | Detected in heart, kidney, liver, lung, pancreas, small intestine, spleen, stomach, thymus and testis. {ECO:0000269|PubMed:12054529}. |
Top Pathways | Apoptosis, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Prion diseases, Protein processing in endoplasmic reticulum |
Anti-Caspase-12 antibody - ab62484 from Abcam
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Anti-Caspase-12 antibody - ab18766 from Abcam
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Anti-Caspase-12 antibody - ab62463 from Abcam
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Anti-Caspase-12 antibody - ab87348 from Abcam
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Anti-Caspase-12 antibody - ab140882 from Abcam
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Anti-Caspase-12 antibody [14F7] - ab10455 from Abcam
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Anti-CASP12 / Caspase 12 Antibody (aa71-84) - LS-C313224 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody IHC-plus⢠- LS-B3785 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody (aa100-116) IHC-plus⢠- LS-B3645 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody - LS-C12603 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody (aa158) - LS-C21332 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody (aa183-205) - LS-C21336 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody - LS-C21339 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody - LS-C48289 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody - LS-C341 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody (aa2-17) - LS-C188903 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody - LS-C26606 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody (clone G1/G1-4) - LS-C189661 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody (aa172-201, APC) - LS-C213063 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody (aa172-201, Biotin) - LS-C213064 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody (aa100-117) - LS-C148598 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody (aa172-201, AP) - LS-C213065 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody (Pro99) - LS-C177601 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody (aa172-201, FITC) - LS-C213066 from LifeSpan Bioscience
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Anti-CASP12 / Caspase 12 Antibody (aa172-201, Azide-free, HRP) - LS-C213067 from LifeSpan Bioscience
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