Gene Symbol | CASP12 |
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Entrez Gene | 100506742 |
Alt Symbol | CASP-12, CASP12P1 |
Species | Human |
Gene Type | protein-coding |
Description | caspase 12 (gene/pseudogene) |
Other Description | caspase 12 pseudogene 1|inactive caspase-12 |
Swissprots | Q6UXS9 D6RBN7 |
Accessions | Q6UXS9 AF464191 AF464192 AF464193 AF464194 AF464195 AF486844 AF486845 AF486846 AF486847 AY358222 AAQ88589 BG183061 NM_001191016 NP_001177945 NR_034061 NR_034063 NR_034064 NR_034065 NR_034066 NR_034067 NR_034068 NR_034070 NR_034071 NR_000035 |
Function | Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF. {ECO:0000269|PubMed:12054529, ECO:0000269|PubMed:15129283}. |
Tissue Specificity | Detected in heart, kidney, liver, lung, pancreas, small intestine, spleen, stomach, thymus and testis. {ECO:0000269|PubMed:12054529}. |
Top Pathways | Apoptosis, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Prion diseases, Protein processing in endoplasmic reticulum |
Caspase-12 peptide - ab38276 from Abcam
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Mouse Caspase-12 peptide - ab8374 from Abcam
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Mouse Caspase-12 peptide - ab8375 from Abcam
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Mouse Caspase-12 peptide - ab98329 from Abcam
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CASP12 / Caspase 12 Antibody Blocking Peptide - LS-E1373 from LifeSpan Bioscience
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CASP12 / Caspase 12 Antibody Blocking Peptide - LS-E30036 from LifeSpan Bioscience
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CASP12 / Caspase 12 Antibody Blocking Peptide - LS-E30035 from LifeSpan Bioscience
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CASP12 / Caspase 12 Antibody Blocking Peptide - LS-E29945 from LifeSpan Bioscience
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CASP12 / Caspase 12 Antibody Blocking Peptide - LS-E27954 from LifeSpan Bioscience
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CASP12-Antibody-Center-Blocking-peptide - BP12027c from Abgent, a WuXi AppTec company
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Caspase-12 Inhibitor Z-ATAD-FMK - FMK013 from R&D Systems
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Caspase 12 Peptide - AC21-2723-P from Abcore
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CASP12 Peptide - 43-089P from ProSci
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Recombinant Human CASP12 - CASP12-897H from Creative Biomart
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Recombinant Caspase 12 (CASP12) - RPA682Mu01 from Uscn Life Science Inc.
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Recombinant Caspase 12 (CASP12) - RPA682Ra01 from Uscn Life Science Inc.
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Caspase 12 Blocking Peptide - CBP2847 from Cohesion Biosciences
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Caspase 12 (P99) Peptide - BS3542P from Bioworld Technology
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Recombinant Human Inactive caspase-12(CASP12) - CSB-YP747641HU CSB-EP747641HU CSB-BP747641HU CSB-MP747641HU from Cusabio
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Caspase 12, Peptide - MBS427911 from MyBioSource
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CASP12 Peptide, Human - M34GP02391H from Creative Peptides
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Inactive caspase-12 (CASP12), Recombinant Protein - MBS1280848 from MyBioSource
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