FBXL5

Gene Symbol	FBXL5
Entrez Gene	26234
Alt Symbol	FBL4, FBL5, FLR1
Species	Human
Gene Type	protein-coding
Description	F-box and leucine-rich repeat protein 5
Other Description	F-box protein FBL4/FBL5|F-box protein FBL5|F-box/LRR-repeat protein 5|p45SKP2-like protein
Swissprots	Q9P0X5 Q9UKC8 Q9UKA1 B4DIB5 Q4W5A8 Q9UJT7 Q9NXN2 Q9P0I0 A8MSK4 Q8NHP3
Accessions	AAY40929 EAW92736 EAW92737 EAW92738 EAW92739 Q9UKA1 AF052097 AF142481 AAF66616 AF157323 AAF67489 AF174591 AAF04512 AF176700 AAF03700 AF199420 AAF09249 AI858616 AK000153 BAA90978 AK295510 BAG58427 AK310860 AL832808 AM392665 CAL37543 AM393475 CAL38352 BC012320 BC030656 AAH30656 BF432189 BI464829 BQ008436 BX537957 CAD97924 DB080171 DQ892452 ABM83378 DQ895664 ABM86590 XM_006713959 XP_006714022 XM_011513831 XP_011512133 XM_011513832 XP_011512134 XM_011513833 XP_011512135 NM_001193534 NP_001180463 NM_001193535 NP_001180464 NM_012161 NP_036293 NR_036464
Function	Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued. {ECO:0000269|PubMed:17532294, ECO:0000269|PubMed:19762596, ECO:0000269|PubMed:19762597}.
Subcellular Location	Cytoplasm, perinuclear region {ECO:0000269|PubMed:17532294}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FBXL5 full length protein - ab132763 from Abcam Category Protein Source Wheat germ Species Human

Human FBXL5 protein fragment - ab161938 from Abcam Category Protein Source Wheat germ Species Human

FBXL5 / FBL5 Antibody Blocking Peptide - LS-E15869 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FBXL5 / FBL5 Antibody Blocking Peptide - LS-E15868 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FBXL5 / FBL5 Antibody Blocking Peptide - LS-E10114 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human FBXL5 Protein - H00026234-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human FBXL5 Protein - H00026234-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

FBXL5-Antibody-N-term-Blocking-peptide - BP9409a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FBXL5 Blocking Peptide - 33R-5399 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FBXL5 Blocking Peptide - 33R-9586 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FBXL5 - H00026234-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

FBXL5 - H00026234-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

FBXL5 - H00026234-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

FBXL5 - H00026234-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

FBXL5 fusion protein - Ag14497 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

FBXL5 fusion protein - ag14101 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human FBXL5, His-tagged - FBXL5-12780H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human F-box/LRR-repeat protein 5(FBXL5) - CSB-YP892451HU CSB-EP892451HU CSB-BP892451HU CSB-MP892451HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FBXL5 Peptide, Human - M34GP05580H from Creative Peptides Category Peptide Source Synthetic. Species Human

F-box/LRR-repeat protein 5 (FBXL5), Recombinant Protein - MBS1316660 from MyBioSource Category Protein Prices $1,495.00, $1,495.00, $1,725.00, $1,725.00, $2,555.00, $2,555.00, $3,000.00, $3,000.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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