LRRC8B

Gene Symbol LRRC8B
Entrez Gene 23507
Alt Symbol TA-LRRP, TALRRP
Species Human
Gene Type protein-coding
Description leucine rich repeat containing 8 family, member B
Other Description T cell activation leucine repeat rich protein|T-cell activation leucine repeat-rich protein|leucine-rich repeat-containing protein 8B|volume-regulated anion channel subunit LRRC8B
Swissprots Q6UY21 D3DT28 Q8N106 Q92627 Q6P9F7
Accessions EAW73137 EAW73138 Q6P9F7 AF385436 AAM43837 AW022123 AY358112 AAQ88479 AY640232 AAU14245 BC030607 AAH30607 BC035081 BC037831 AAH37831 BC053565 BC060782 AAH60782 BI459217 D86984 BAA13220 XM_005270701 XP_005270758 XM_005270702 XP_005270759 XM_005270703 XP_005270760 XM_011541143 XP_011539445 XM_011541144 XP_011539446 XM_011541145 XP_011539447 XM_011541146 XP_011539448 XM_011541147 XP_011539449 XM_011541148 XP_011539450 NM_001134476 NP_001127948 NM_015350 NP_056165
Function Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8B constitutes a pore-forming subunit or whether it is closely associated with the pore (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Human LRRC8B full length protein - ab161669 from Abcam

Category Protein
Source Wheat germ
Species Human
ab161669 on a 12.5% SDS-PAGE stained with Coomassie Blue.

LRRC8B Antibody Blocking Peptide - LS-E2857 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

LRRC8B Antibody Blocking Peptide - LS-E17105 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

LRRC8B Antibody Blocking Peptide - LS-E17104 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human LRRC8B Protein - H00023507-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

LRRC8B-Antibody-N-term--Blocking-peptide - BP13978a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

LRRC8B Blocking Peptide - 33R-7375 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

LRRC8B Blocking Peptide - 33R-9195 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

LRRC8B - H00023507-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

LRRC8B - H00023507-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

LRRC8B Recombinant Protein Antigen - NBP1-81532PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

LRRC8B Peptide, Human - M34GP08930H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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