LRRC8B

Gene Symbol	LRRC8B
Entrez Gene	23507
Alt Symbol	TA-LRRP, TALRRP
Species	Human
Gene Type	protein-coding
Description	leucine rich repeat containing 8 family, member B
Other Description	T cell activation leucine repeat rich protein|T-cell activation leucine repeat-rich protein|leucine-rich repeat-containing protein 8B|volume-regulated anion channel subunit LRRC8B
Swissprots	Q6UY21 D3DT28 Q8N106 Q92627 Q6P9F7
Accessions	EAW73137 EAW73138 Q6P9F7 AF385436 AAM43837 AW022123 AY358112 AAQ88479 AY640232 AAU14245 BC030607 AAH30607 BC035081 BC037831 AAH37831 BC053565 BC060782 AAH60782 BI459217 D86984 BAA13220 XM_005270701 XP_005270758 XM_005270702 XP_005270759 XM_005270703 XP_005270760 XM_011541143 XP_011539445 XM_011541144 XP_011539446 XM_011541145 XP_011539447 XM_011541146 XP_011539448 XM_011541147 XP_011539449 XM_011541148 XP_011539450 NM_001134476 NP_001127948 NM_015350 NP_056165
Function	Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8B constitutes a pore-forming subunit or whether it is closely associated with the pore (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LRRC8B full length protein - ab161669 from Abcam Category Protein Source Wheat germ Species Human

LRRC8B Antibody Blocking Peptide - LS-E2857 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LRRC8B Antibody Blocking Peptide - LS-E17105 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LRRC8B Antibody Blocking Peptide - LS-E17104 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human LRRC8B Protein - H00023507-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

LRRC8B-Antibody-N-term--Blocking-peptide - BP13978a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

LRRC8B Blocking Peptide - 33R-7375 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

LRRC8B Blocking Peptide - 33R-9195 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

LRRC8B - H00023507-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

LRRC8B - H00023507-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

LRRC8B Recombinant Protein Antigen - NBP1-81532PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

LRRC8B Peptide, Human - M34GP08930H from Creative Peptides Category Peptide Source Synthetic. Species Human

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