LRRC8B

Gene Symbol LRRC8B
Entrez Gene 23507
Alt Symbol TA-LRRP, TALRRP
Species Human
Gene Type protein-coding
Description leucine rich repeat containing 8 family, member B
Other Description T cell activation leucine repeat rich protein|T-cell activation leucine repeat-rich protein|leucine-rich repeat-containing protein 8B|volume-regulated anion channel subunit LRRC8B
Swissprots Q6UY21 D3DT28 Q8N106 Q92627 Q6P9F7
Accessions EAW73137 EAW73138 Q6P9F7 AF385436 AAM43837 AW022123 AY358112 AAQ88479 AY640232 AAU14245 BC030607 AAH30607 BC035081 BC037831 AAH37831 BC053565 BC060782 AAH60782 BI459217 D86984 BAA13220 XM_005270701 XP_005270758 XM_005270702 XP_005270759 XM_005270703 XP_005270760 XM_011541143 XP_011539445 XM_011541144 XP_011539446 XM_011541145 XP_011539447 XM_011541146 XP_011539448 XM_011541147 XP_011539449 XM_011541148 XP_011539450 NM_001134476 NP_001127948 NM_015350 NP_056165
Function Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8B constitutes a pore-forming subunit or whether it is closely associated with the pore (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

LRRC8B CRISPR/Cas9 KO Plasmid (h) - sc-411752 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8B HDR Plasmid (h) - sc-411752-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8B Double Nickase Plasmid (h) - sc-411752-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8B Double Nickase Plasmid (h2) - sc-411752-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8B CRISPR Activation Plasmid (h) - sc-411752-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8B CRISPR Activation Plasmid (h2) - sc-411752-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8B Lentiviral Activation Particles (h) - sc-411752-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8B Lentiviral Activation Particles (h2) - sc-411752-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC8B siRNA (h) - sc-88817 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LRRC8B shRNA Plasmid (h) - sc-88817-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LRRC8B shRNA (h) Lentiviral Particles - sc-88817-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU105351 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN12765 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12765 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05236 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05236

LRRC8B siRNA (Human) - CRH8313 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human LRRC8B (NM_015350.2) - SHH334855 from Creative biogene

Category siRNA
Species Reactivities Human

Human LRRC8B siRNA - orb268815 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LRRC8B shRNA Plasmid (Human) - CHH8313 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LRRC8B miRNA 3'UTR clone - MiUTR4H-TG05155 from Creative biogene

Species Reactivities Human
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