LRRC8B

Gene Symbol LRRC8B
Entrez Gene 23507
Alt Symbol TA-LRRP, TALRRP
Species Human
Gene Type protein-coding
Description leucine rich repeat containing 8 family, member B
Other Description T cell activation leucine repeat rich protein|T-cell activation leucine repeat-rich protein|leucine-rich repeat-containing protein 8B|volume-regulated anion channel subunit LRRC8B
Swissprots Q6UY21 D3DT28 Q8N106 Q92627 Q6P9F7
Accessions EAW73137 EAW73138 Q6P9F7 AF385436 AAM43837 AW022123 AY358112 AAQ88479 AY640232 AAU14245 BC030607 AAH30607 BC035081 BC037831 AAH37831 BC053565 BC060782 AAH60782 BI459217 D86984 BAA13220 XM_005270701 XP_005270758 XM_005270702 XP_005270759 XM_005270703 XP_005270760 XM_011541143 XP_011539445 XM_011541144 XP_011539446 XM_011541145 XP_011539447 XM_011541146 XP_011539448 XM_011541147 XP_011539449 XM_011541148 XP_011539450 NM_001134476 NP_001127948 NM_015350 NP_056165
Function Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8B constitutes a pore-forming subunit or whether it is closely associated with the pore (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

LRRC8B (N-12) - sc-164924 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LRRC8B (N-12): sc-164924. Western blot analysis of LRRC8B expression in mouse brain (A) and mouse cerebellum (B) tissue extracts.

LRRC8B (I-15) - sc-164923 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-LRRC8B antibody - ab87575 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-LRRC8B antibody (ab87575) at 1 µg/ml + Human fetal stomach lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-LRRC8B antibody - ab116516 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-LRRC8B antibody (ab116516) at 1/100 dilution + NCI-H292 cell line lysate at 35 µg

Anti-LRRC8B Antibody (aa542-591) IHC-plus™ - LS-B4665 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LRRC8B antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4665 concentration 5 ug/ml.

Anti-LRRC8B Antibody (aa222-252, AP) - LS-C262265 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC8B Antibody (aa222-252, APC) - LS-C262266 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC8B Antibody (aa222-252, FITC) - LS-C262268 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC8B Antibody (aa222-252, Biotin) - LS-C262267 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC8B Antibody (aa222-252, Azide-free, HRP) - LS-C262269 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC8B Antibody (aa222-252, PE) - LS-C262270 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC8B Antibody (aa222-252) - LS-C322744 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC8B Antibody (aa143-192) - LS-C111133 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LRRC8B antibody LS-C111133 Western blot of Fetal Stomach lysate.

Anti-LRRC8B Antibody (aa223-252) - LS-C165892 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
LRRC8B Antibody (N-term ) immunohistochemistry of formalin-fixed and paraffin-embedded human cerebellum tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

LRRC8B Antibody - NBP1-59968 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

LRRC8B Antibody - NBP1-59628 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: LRRC8B Antibody [NBP1-59628] - Human Fetal Liver tissue lysate at a concentration of 1ug/ml.

LRRC8B Antibody - NBP1-81532 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC8B, (N-terminal) antibody produced in rabbit - SAB2103512 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-LRRC8B, antibody produced in rabbit: <B>Cat. No. SAB2103512</B>: Immunoblotting analysis of LRRC8B in fetal stomach tissue lysate with LRRC8B anitbody at 1 μg/mL.

Anti-LRRC8B antibody produced in rabbit - SAB2101394 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-LRRC8B: <B>Cat. No.SAB2101394</B>: LRRC8B in Fetal Liver tissue lysate with LRRC8B antibody at 1.0 μg/mL.

LRRC8B antibody - middle region (ARP47145_P050) - ARP47145_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LRRC8B antibody - N-terminal region (ARP47146_P050) - ARP47146_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LRRC8B-Antibody-N-term- - AP13978a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
LRRC8B Antibody (N-term ) (Cat. #AP13978a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the LRRC8B antibody detected the LRRC8B protein (arrow).

LRRC8B antibody, Internal - GTX46360 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

LRRC8B antibody, N-term - GTX46359 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

LRRC8B Antibody - N-terminal region (OAAB10276) - OAAB10276 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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