Gene Symbol | LMAN2 |
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Entrez Gene | 10960 |
Alt Symbol | C5orf8, GP36B, VIP36 |
Species | Human |
Gene Type | protein-coding |
Description | lectin, mannose-binding 2 |
Other Description | glycoprotein GP36b|vesicular integral protein of 36 kDa|vesicular integral-membrane protein 36|vesicular integral-membrane protein VIP36 |
Swissprots | Q53HH1 Q12907 |
Accessions | EAW85014 EAW85015 Q12907 AK222609 BAD96329 AK292099 BAF84788 AK301607 BAG63093 AK308027 BC017263 AAH17263 DC404202 JF432530 ADZ15747 U10362 AAA19572 NM_006816 NP_006807 |
Function | Plays a role as an intracellular lectin in the early secretory pathway. Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans. Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:10444376}; Single-pass type I membrane protein {ECO:0000269|PubMed:10444376}. Golgi apparatus membrane {ECO:0000269|PubMed:10444376}; Single-pass membrane protein {ECO:0000269|PubMed:10444376}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:10444376}; Single-pass type I membrane protein {ECO:0000269|PubMed:10444376}. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Protein processing in endoplasmic reticulum |
VIP36 (H-90) - sc-67131 from Santa Cruz Biotechnology
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VIP36 (V-20) - sc-32441 from Santa Cruz Biotechnology
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VIP36 (264C4a) - sc-130026 from Santa Cruz Biotechnology
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Anti-LMAN2 antibody - ab124146 from Abcam
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Anti-LMAN2 antibody [264C4a] - ab67000 from Abcam
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Anti-LMAN2 / VIP36 Antibody - LS-C71580 from LifeSpan Bioscience
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Anti-LMAN2 / VIP36 Antibody (clone 264C4a) - LS-C184628 from LifeSpan Bioscience
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Anti-LMAN2 / VIP36 Antibody (aa284-314, Biotin) - LS-C223054 from LifeSpan Bioscience
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Anti-LMAN2 / VIP36 Antibody (aa284-314, APC) - LS-C223053 from LifeSpan Bioscience
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Anti-LMAN2 / VIP36 Antibody (aa284-314, AP) - LS-C223052 from LifeSpan Bioscience
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Anti-LMAN2 / VIP36 Antibody (aa284-314, FITC) - LS-C223055 from LifeSpan Bioscience
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Anti-LMAN2 / VIP36 Antibody (aa284-314, Azide-free, HRP) - LS-C223056 from LifeSpan Bioscience
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Anti-LMAN2 / VIP36 Antibody (aa284-314, PE) - LS-C223057 from LifeSpan Bioscience
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Anti-LMAN2 / VIP36 Antibody (aa284-314) - LS-C329771 from LifeSpan Bioscience
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Anti-LMAN2 / VIP36 Antibody (aa276-325) - LS-C80933 from LifeSpan Bioscience
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Anti-LMAN2 / VIP36 Antibody (aa67-116) - LS-C186719 from LifeSpan Bioscience
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Anti-LMAN2 / VIP36 Antibody (clone 264C4a) - LS-C342659 from LifeSpan Bioscience
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Anti-LMAN2 / VIP36 Antibody (aa285-314) - LS-C165805 from LifeSpan Bioscience
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Anti-LMAN2 / VIP36 Antibody (aa59-108) - LS-C80932 from LifeSpan Bioscience
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LMAN2 Antibody - NBP2-17153 from Novus Biologicals
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LMAN2 Antibody - NBP1-69475 from Novus Biologicals
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LMAN2 Antibody - NBP1-69474 from Novus Biologicals
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Anti-LMAN2 (AB1) antibody produced in rabbit - AV46788 from Sigma-Aldrich
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Anti-LMAN2 antibody produced in rabbit - HPA003927 from Sigma-Aldrich
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Anti-VIP36/ LMAN2 antibody produced in rabbit - SAB4200233 from Sigma-Aldrich
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