Bad

Gene Symbol	Bad
Entrez Gene	12015
Alt Symbol	AI325008, Bbc2
Species	Mouse
Gene Type	protein-coding
Description	BCL2-associated agonist of cell death
Other Description	bcl-2-binding component 6|bcl-xL/Bcl-2-associated death promoter|bcl2 antagonist of cell death|bcl2-associated agonist of cell death
Swissprots	Q61337
Accessions	EDL33265 EDL33266 Q61337 AK029400 AK131666 BAE20753 AK151792 BAE30693 AK169002 BAE40801 BC006762 AAH06762 L37296 AAA64465 NM_001285453 NP_001272382 NM_007522 NP_031548
Function	Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Subcellular Location	Mitochondrion outer membrane. Cytoplasm {ECO:0000269|PubMed:21546903}. Note=Colocalizes with HIF3A isoform 2 in the cytoplasm (PubMed:21546903). Upon phosphorylation, locates to the cytoplasm. {ECO:0000269|PubMed:21546903}.
Top Pathways	Apoptosis, Hepatitis C, cGMP-PKG signaling pathway, PI3K-Akt signaling pathway, Viral carcinogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Mouse-BAD-Antibody-C-term-S161-Blocking-peptide - BP18704b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg Species Mouse

mouse-BAD-Antibody-Center-Y76-Blocking-Peptide - BP18697c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg Species Mouse

mouse-BAD-Antibody-Center-T94-Blocking-Peptide - BP18696c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg Species Mouse

mouse-BAD-Antibody-Center-S112S111Y113-Blocking-Peptide - BP18695c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg Species Mouse

Mouse-BAD-Antibody-C-term-T201-Blocking-Peptide - BP18613c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg Species Mouse

mouse-BAD-Antibody-Center-S134-Blocking-Peptide - BP19245c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg Species Mouse

Phospho-mouse-BADT94-Antibody-Blocking-peptide - BP3777s from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg Species Mouse

Phospho-mouse-BADS161-Antibody-Blocking-peptide - BP3777c from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg Species Mouse

Phospho-mouse-BADS112-Antibody-Blocking-peptide - BP3777b from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg Species Mouse

Phospho-mouse-BADS111-Antibody-Blocking-peptide - BP3777a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg Species Mouse

BAD-BH3-146-159 - SP2404b from Abgent, a WuXi AppTec company Category Peptide Prices $300.00 Sizes 5 mg

BAD-BH3-146-159 - SP2404a from Abgent, a WuXi AppTec company Category Peptide Prices $132.00 Sizes 1 mg

Recombinant Mouse Bcl2 antagonist of cell death(Bad) - CSB-YP736816MO CSB-EP736816MO CSB-BP736816MO CSB-MP736816MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Recombinant Mouse BAD Protein - BAD-2269M from Creative Biomart Category Protein Source Mammalian Cells Species Mouse

Phospho-mouse-BADY113-Blocking-Peptide - BP3777k from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg Species Mouse

Phospho-mouse-BADS96-Blocking-Peptide - BP3849a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg Species Mouse

Phospho-mouse-BADS134-Blocking-Peptide - BP3777o from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg Species Mouse

Bcl2 antagonist of cell death (Bad), Recombinant Protein - MBS1345209 from MyBioSource Category Protein Prices $955.00, $955.00, $1,175.00, $1,175.00, $1,425.00, $1,425.00, $1,890.00, $1,890.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Mouse

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