Bad

Gene Symbol	Bad
Entrez Gene	12015
Alt Symbol	AI325008, Bbc2
Species	Mouse
Gene Type	protein-coding
Description	BCL2-associated agonist of cell death
Other Description	bcl-2-binding component 6|bcl-xL/Bcl-2-associated death promoter|bcl2 antagonist of cell death|bcl2-associated agonist of cell death
Swissprots	Q61337
Accessions	EDL33265 EDL33266 Q61337 AK029400 AK131666 BAE20753 AK151792 BAE30693 AK169002 BAE40801 BC006762 AAH06762 L37296 AAA64465 NM_001285453 NP_001272382 NM_007522 NP_031548
Function	Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Subcellular Location	Mitochondrion outer membrane. Cytoplasm {ECO:0000269|PubMed:21546903}. Note=Colocalizes with HIF3A isoform 2 in the cytoplasm (PubMed:21546903). Upon phosphorylation, locates to the cytoplasm. {ECO:0000269|PubMed:21546903}.
Top Pathways	Apoptosis, Hepatitis C, cGMP-PKG signaling pathway, PI3K-Akt signaling pathway, Viral carcinogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Phospho-Bad (Ser112) (40A9) Rabbit mAb (PE Conjugate) - 11865 from Cell Signaling Technology Prices $299.00 Sizes 100 µl (50 tests) Host Rabbit Clonality Monoclonal Clone 40A9

PhosphoPlus® Bad (Ser112/136) Antibody Kit - 9290 from Cell Signaling Technology Clonality Polyclonal

Bad (C-20) - sc-943 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-Bad antibody - ab90435 from Abcam Prices $384.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Bad antibody - ab7975 from Abcam Host Rabbit Clonality Polyclonal

Anti-Bad antibody [64103] - ab10520 from Abcam Prices $368.00 Sizes 50 µg Host Rat Clonality Monoclonal Clone 64103

cleaved BAD Antibody - NBP1-71371 from Novus Biologicals Prices $229.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Bad [p Ser155] Antibody (27AT381) - NB100-94179 from Novus Biologicals Prices $419.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 27AT381

Bad [p Ser155] Antibody (27AT937) - NB100-94166 from Novus Biologicals Prices $449.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 27AT937

BAD (Ser128) Polyclonal Antibody - bs-0893R from Bioss Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

BAD (Ser128) Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-0893R-A350 from Bioss Prices $389.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

BAD (Ser128) Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-0893R-A488 from Bioss Prices $389.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

BAD (Ser128) Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-0893R-A555 from Bioss Prices $389.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

BAD (Ser128) Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-0893R-A647 from Bioss Prices $389.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

BAD (Ser128) Polyclonal Antibody, Cy3 Conjugated - bs-0893R-Cy3 from Bioss Prices $389.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

BAD (Ser128) Polyclonal Antibody, Cy5 Conjugated - bs-0893R-Cy5 from Bioss Prices $389.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

BAD (Ser128) Polyclonal Antibody, Cy5.5 Conjugated - bs-0893R-Cy5.5 from Bioss Prices $389.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

BAD (Ser128) Polyclonal Antibody, Cy7 Conjugated - bs-0893R-Cy7 from Bioss Prices $389.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

BAD (Ser128) Polyclonal Antibody, FITC Conjugated - bs-0893R-FITC from Bioss Prices $389.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

BAD (Ser128) Polyclonal Antibody, Biotin Conjugated - bs-0893R-Biotin from Bioss Prices $369.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

BAD (Ser128) Polyclonal Antibody, HRP Conjugated - bs-0893R-HRP from Bioss Prices $389.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Monoclonal Anti-Bad antibody produced in rat - B0559 from Sigma-Aldrich Prices $399.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone 64103

MONOCLONAL ANTI-PHOSPHO-MBAD(SER155) antibody produced in mouse - SAB1305485 from Sigma-Aldrich Prices $326.00 Sizes 40 tst Host Mouse Clonality Monoclonal Clone 27AT937

MONOCLONAL ANTI-PHOSPHO-MBAD(SER155) antibody produced in mouse - SAB1305489 from Sigma-Aldrich Prices $326.00 Sizes 40 tst Host Mouse Clonality Monoclonal Clone 27AT381

Anti-BAD (Cleaved-Asp71) antibody produced in rabbit - SAB4500297 from Sigma-Aldrich Prices $335.50 Sizes 100 µg Host Rabbit Clonality Polyclonal

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