Bad

Gene Symbol Bad
Entrez Gene 12015
Alt Symbol AI325008, Bbc2
Species Mouse
Gene Type protein-coding
Description BCL2-associated agonist of cell death
Other Description bcl-2-binding component 6|bcl-xL/Bcl-2-associated death promoter|bcl2 antagonist of cell death|bcl2-associated agonist of cell death
Swissprots Q61337
Accessions EDL33265 EDL33266 Q61337 AK029400 AK131666 BAE20753 AK151792 BAE30693 AK169002 BAE40801 BC006762 AAH06762 L37296 AAA64465 NM_001285453 NP_001272382 NM_007522 NP_031548
Function Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Subcellular Location Mitochondrion outer membrane. Cytoplasm {ECO:0000269|PubMed:21546903}. Note=Colocalizes with HIF3A isoform 2 in the cytoplasm (PubMed:21546903). Upon phosphorylation, locates to the cytoplasm. {ECO:0000269|PubMed:21546903}.
Top Pathways Apoptosis, Hepatitis C, cGMP-PKG signaling pathway, PI3K-Akt signaling pathway, Viral carcinogenesis

Bad CRISPR/Cas9 KO Plasmid (m) - sc-419285 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bad HDR Plasmid (m) - sc-419285-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bad Double Nickase Plasmid (m) - sc-419285-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bad Double Nickase Plasmid (m2) - sc-419285-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bad CRISPR Activation Plasmid (m) - sc-419285-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bad CRISPR Activation Plasmid (m2) - sc-419285-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bad Lentiviral Activation Particles (m) - sc-419285-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bad Lentiviral Activation Particles (m2) - sc-419285-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bad siRNA (m) - sc-29779 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Bad shRNA Plasmid (m) - sc-29779-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Bad shRNA (m) Lentiviral Particles - sc-29779-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN27383 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND27383 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

BAD siRNA (Mouse) - CRM0339 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

BAD - MBS8230323 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse BAD (NM_007522.2) - SHH244610 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Bad(NM_007522.2) - SHG090089 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse BAD siRNA - orb279815 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

BAD shRNA Plasmid (Mouse) - CHM0339 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

BAD miRNA 3'UTR clone - MiUTR1M-01957 from Creative biogene

Species Reactivities Mouse
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