INPP5K

Gene Symbol	INPP5K
Entrez Gene	51763
Alt Symbol	PPS, SKIP
Species	Human
Gene Type	protein-coding
Description	inositol polyphosphate-5-phosphatase K
Other Description	inositol polyphosphate 5-phosphatase K|skeletal muscle and kidney-enriched inositol phosphatase
Swissprots	Q9P2R5 Q9NPJ5 B2R750 Q15733 D3DTH8 Q9BT40 B2R6I2
Accessions	BAA92342 EAW90614 EAW90615 EAW90616 EAW90617 EAW90618 Q9BT40 AB036829 BAA92340 AB036830 BAA92341 AK297955 BAH12695 AK303907 BAH14079 AK307293 AK312585 BAG35479 AK312844 BAG35697 BC004362 AAH04362 BG722885 BM510617 DQ892815 ABM83741 DQ896061 ABM87060 U45973 AAB03214 XM_005256683 XP_005256740 XM_005256685 XP_005256742 XM_005256686 XP_005256743 XM_011523934 XP_011522236 XM_011523935 XP_011522237 XM_011523936 XP_011522238 NM_001135642 NP_001129114 NM_016532 NP_057616 NM_130766 NP_570122
Function	Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5- trisphosphate. May negatively regulate assembly of the actin cytoskeleton. {ECO:0000269|PubMed:10753883}.
Subcellular Location	Endoplasmic reticulum {ECO:0000269|PubMed:12536145}. Note=Following stimulation with EGF, translocates to membrane ruffles.
Tissue Specificity	Ubiquitously expressed with highest levels in skeletal muscle, heart and kidney. {ECO:0000269|PubMed:10753883}.
Top Pathways	Insulin signaling pathway, Inositol phosphate metabolism, Phosphatidylinositol signaling system

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SKIP 293T Cell Transient Overexpression Lysate(Denatured) - H00051763-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

INPP5K overexpression lysate - LY408929 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

INPP5K overexpression lysate - LY427643 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

INPP5K 293 Cell Lysate - 402239 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

INPP5K 293 Cell Lysate - 404803 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

SKIP Overexpression Lysate (Native) - NBL1-15991 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SKIP Overexpression Lysate (Native) - NBL1-15992 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SKIP (h): 293T Lysate - sc-159714 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

SKIP (h3): 293T Lysate - sc-158962 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

INPP5K Over-expression Lysate Product - GWB-7F7A4F from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

INPP5K Over-expression Lysate Product - GWB-37F1EE from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

SKIP Overexpression Lysate (Native) - NBP2-11097 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SKIP Overexpression Lysate (Denatured) - H00051763-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

INPP5K-knockout Cell lysate - LC810360 from Acris Antibodies Category Cell Lysate Prices $495.00 Sizes 100 µg

Panoply™ Human INPP5K Knockdown Stable Cell Line - CSC-DC007668 from Creative biogene Category Cell Line Species Human

Human INPP5K Knockout Cell Line-HeLa - CSC-RT1502 from Creative biogene Category Cell Line Species Human

Human INPP5K Knockout Cell Line-HeLa - CSC-RT1661 from Creative biogene Category Cell Line Species Human

INPP5K KO Cell Lysate-HeLa - CLKO-1350 from Creative biogene Category Cell Lysate

INPP5K KO Cell Lysate-HeLa - CLKO-1508 from Creative biogene Category Cell Lysate

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