INPP5K

Gene Symbol	INPP5K
Entrez Gene	51763
Alt Symbol	PPS, SKIP
Species	Human
Gene Type	protein-coding
Description	inositol polyphosphate-5-phosphatase K
Other Description	inositol polyphosphate 5-phosphatase K|skeletal muscle and kidney-enriched inositol phosphatase
Swissprots	Q9P2R5 Q9NPJ5 B2R750 Q15733 D3DTH8 Q9BT40 B2R6I2
Accessions	BAA92342 EAW90614 EAW90615 EAW90616 EAW90617 EAW90618 Q9BT40 AB036829 BAA92340 AB036830 BAA92341 AK297955 BAH12695 AK303907 BAH14079 AK307293 AK312585 BAG35479 AK312844 BAG35697 BC004362 AAH04362 BG722885 BM510617 DQ892815 ABM83741 DQ896061 ABM87060 U45973 AAB03214 XM_005256683 XP_005256740 XM_005256685 XP_005256742 XM_005256686 XP_005256743 XM_011523934 XP_011522236 XM_011523935 XP_011522237 XM_011523936 XP_011522238 NM_001135642 NP_001129114 NM_016532 NP_057616 NM_130766 NP_570122
Function	Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5- trisphosphate. May negatively regulate assembly of the actin cytoskeleton. {ECO:0000269|PubMed:10753883}.
Subcellular Location	Endoplasmic reticulum {ECO:0000269|PubMed:12536145}. Note=Following stimulation with EGF, translocates to membrane ruffles.
Tissue Specificity	Ubiquitously expressed with highest levels in skeletal muscle, heart and kidney. {ECO:0000269|PubMed:10753883}.
Top Pathways	Insulin signaling pathway, Inositol phosphate metabolism, Phosphatidylinositol signaling system

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SKIP CRISPR/Cas9 KO Plasmid (h) - sc-407373 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SKIP HDR Plasmid (h) - sc-407373-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SKIP Double Nickase Plasmid (h) - sc-407373-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SKIP Double Nickase Plasmid (h2) - sc-407373-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SKIP CRISPR Activation Plasmid (h) - sc-407373-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SKIP CRISPR Activation Plasmid (h2) - sc-407373-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SKIP Lentiviral Activation Particles (h) - sc-407373-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SKIP Lentiviral Activation Particles (h2) - sc-407373-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SKIP siRNA (h) - sc-106937 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

SKIP shRNA Plasmid (h) - sc-106937-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

SKIP shRNA (h) Lentiviral Particles - sc-106937-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

SKIP RNAi - H00051763-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

SKIP RNAi - H00051763-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU068521 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0861 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0860 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0859 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN10696 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10696 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09123 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr09123

INPP5K siRNA (Human) - CRH9940 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

INPP5K - MBS8222776 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SKIP CRISPR/Cas9 KO Plasmid (h2) - sc-407373-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SKIP HDR Plasmid (h2) - sc-407373-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human INPP5K (NM_016532.3) - SHH319765 from Creative biogene Category siRNA Species Reactivities Human

Search more