Gene Symbol | TIMM50 |
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Entrez Gene | 92609 |
Alt Symbol | TIM50, TIM50L |
Species | Human |
Gene Type | protein-coding |
Description | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
Other Description | Tim50-like protein|homolog of yeast Tim50|mitochondrial import inner membrane translocase subunit TIM50 |
Swissprots | Q9H370 Q96FJ5 Q96GY2 Q3ZCQ8 Q330K1 Q6QA00 |
Accessions | EAW56901 EAW56902 EAW56903 Q3ZCQ8 AK092396 AK097291 AK098197 AY444561 AAS68537 AY551341 AAT01208 BC009072 AAH09072 BC010736 AAH10736 BC014674 BC050082 AAH50082 BC121146 AAI21147 BC121147 AAI21148 BE386959 BI856163 BQ925812 BU540967 XM_011527491 XP_011525793 NM_001001563 NP_001001563 |
Function | Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body. {ECO:0000269|PubMed:15044455}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:15044455, ECO:0000269|PubMed:16008839}; Single-pass membrane protein {ECO:0000269|PubMed:15044455, ECO:0000269|PubMed:16008839}. |
Tissue Specificity | Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level). {ECO:0000269|PubMed:15044455, ECO:0000269|PubMed:16008839}. |
Human TIMM50 protein fragment - ab153573 from Abcam
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TIMM50 Antibody Blocking Peptide - LS-E6359 from LifeSpan Bioscience
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TIMM50 Antibody Blocking Peptide - LS-E25775 from LifeSpan Bioscience
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TIMM50 Antibody Blocking Peptide - LS-E24794 from LifeSpan Bioscience
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Recombinant Human TIMM50 Protein - H00092609-Q01 from Novus Biologicals
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TIMM50-Antibody-N-term-Blocking-Peptide - BP19064a from Abgent, a WuXi AppTec company
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TIM50 blocking peptide - GTX89675-PEP from GeneTex
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TIMM50 Peptide - AC21-0604-P from Abcore
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TIMM50 - H00092609-Q01-10 from Acris Antibodies
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TIMM50 - H00092609-Q01-25 from Acris Antibodies
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TIM-50 Peptide - 46-496P from ProSci
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TIMM50 fusion protein - Ag17574 from Proteintech Group
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TIMM50 fusion protein - Ag17594 from Proteintech Group
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Recombinant Human TIMM50, GST-tagged - TIMM50-3238H from Creative Biomart
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TIM50, Peptide - MBS425520 from MyBioSource
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TIMM50 Recombinant Protein Antigen - NBP2-38791PEP from Novus Biologicals
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TIMM50-Blocking-Peptide-N-term - BP20709a from Abgent, a WuXi AppTec company
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TIMM50 Peptide, Human - M34GP15964H from Creative Peptides
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TIMM50 Immunizing peptide - orb17891 from Biorbyt
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Mitochondrial import inner membrane translocase subunit TIM50 (scpl-4), Recombinant Protein - MBS7029325 from MyBioSource
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Mitochondrial import inner membrane translocase subunit TIM50 (TIM50), Recombinant Protein - MBS1169320 from MyBioSource
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Mitochondrial import inner membrane translocase subunit TIM50 (TIM50), Recombinant Protein - MBS7031212 from MyBioSource
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Mitochondrial import inner membrane translocase subunit TIM50 (TIM50), Recombinant Protein - MBS7031213 from MyBioSource
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Mitochondrial import inner membrane translocase subunit TIM50 (TIM50), Recombinant Protein - MBS7031214 from MyBioSource
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Mitochondrial import inner membrane translocase subunit TIM50 (TIM50), Recombinant Protein - MBS7031215 from MyBioSource
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