TIMM50

Gene Symbol	TIMM50
Entrez Gene	92609
Alt Symbol	TIM50, TIM50L
Species	Human
Gene Type	protein-coding
Description	translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
Other Description	Tim50-like protein|homolog of yeast Tim50|mitochondrial import inner membrane translocase subunit TIM50
Swissprots	Q9H370 Q96FJ5 Q96GY2 Q3ZCQ8 Q330K1 Q6QA00
Accessions	EAW56901 EAW56902 EAW56903 Q3ZCQ8 AK092396 AK097291 AK098197 AY444561 AAS68537 AY551341 AAT01208 BC009072 AAH09072 BC010736 AAH10736 BC014674 BC050082 AAH50082 BC121146 AAI21147 BC121147 AAI21148 BE386959 BI856163 BQ925812 BU540967 XM_011527491 XP_011525793 NM_001001563 NP_001001563
Function	Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body. {ECO:0000269|PubMed:15044455}.
Subcellular Location	Mitochondrion inner membrane {ECO:0000269|PubMed:15044455, ECO:0000269|PubMed:16008839}; Single-pass membrane protein {ECO:0000269|PubMed:15044455, ECO:0000269|PubMed:16008839}.
Tissue Specificity	Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level). {ECO:0000269|PubMed:15044455, ECO:0000269|PubMed:16008839}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Tim50 CRISPR/Cas9 KO Plasmid (h) - sc-405970 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Tim50 HDR Plasmid (h) - sc-405970-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Tim50 Double Nickase Plasmid (h) - sc-405970-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Tim50 Double Nickase Plasmid (h2) - sc-405970-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Tim50 CRISPR Activation Plasmid (h) - sc-405970-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Tim50 CRISPR Activation Plasmid (h2) - sc-405970-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Tim50 Lentiviral Activation Particles (h) - sc-405970-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Tim50 Lentiviral Activation Particles (h2) - sc-405970-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Tim50 siRNA (h) - sc-63129 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Tim50 shRNA Plasmid (h) - sc-63129-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Tim50 shRNA (h) Lentiviral Particles - sc-63129-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

TIMM50 RNAi - H00092609-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU043281 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® Human Phosphatase - SIHP0892 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0893 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0894 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN21363 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21363 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

TIMM50 siRNA (Human) - CRJ4152 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TIMM50 - MBS8236413 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human TIMM50 (NM_001001563.1) - SHH427460 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human TIMM50(NM_001001563.1) - SHL071424 from Creative biogene Category siRNA Species Reactivities Human

Human TIMM50 siRNA - orb274653 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TIMM50 shRNA Plasmid (Human) - CHJ4152 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

TIMM50 miRNA 3'UTR clone - MiUTR1H-10414 from Creative biogene Species Reactivities Human

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