GOLPH3

Gene Symbol GOLPH3
Entrez Gene 64083
Alt Symbol GOPP1, GPP34, MIDAS, Vps74
Species Human
Gene Type protein-coding
Description golgi phosphoprotein 3 (coat-protein)
Other Description Golgi phosphoprotein 3|coat protein GPP34|coat-protein|golgi peripheral membrane protein 1, 34 kDa|golgi protein|golgi-associated protein|mitochondrial DNA absence factor
Swissprots Q9UIW5 Q9H4A6
Accessions CAF86422 CCQ43682 EAX10780 EAX10781 EAX10782 Q9H4A6 AJ296152 CAC13124 AK057544 BAG51933 AK075077 BAG52061 AK075156 BAC11438 AK092604 BAG52580 AK128510 BAG54686 AK293368 BAG56882 AK301588 BAG63078 AL133078 CAB61398 BC012123 AAH12123 BC033725 AAH33725 BC063586 AAH63586 NM_022130 NP_071413
Function Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Has also been involved in the control of the localization of Golgi enzymes through interaction with their cytoplasmic part. May play an indirect role in cell migration. Has also been involved in the modulation of mTOR signaling. May also be involved in the regulation of mitochondrial lipids biosynthesis. {ECO:0000269|PubMed:16263763, ECO:0000269|PubMed:19553991, ECO:0000269|PubMed:19837035, ECO:0000269|PubMed:22745132, ECO:0000269|PubMed:23027862, ECO:0000269|PubMed:23345592, ECO:0000269|PubMed:23500462}.
Subcellular Location Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion intermembrane space. Cell membrane {ECO:0000250}. Endosome {ECO:0000250}. Note=Phosphatidylinositol 4-phosphate-binding and oligomerization participate in the recruitment onto Golgi membranes. {ECO:0000305}.
Tissue Specificity Detected in muscle fibers of patients with mitochondrial diseases; not detected in normal muscle fibers.
Top Pathways Transcriptional misregulation in cancer

Anti-GOLPH3 antibody - ab82377 from Abcam

Prices $385.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
IHC-P human prostate carcinoma stained with ab82377, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Anti-GOLPH3 antibody - ab69171 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-GOLPH3 antibody (ab69171) at 1/500 dilutionLane 1 : GOLPH3 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-GOLPH3 antibody - ab113649 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab113649, at 5 µg/ml, staining GOLPH3 in Formalin fixed, Paraffin embedded Human prostate tissue by Immunohistochemistry.

Anti-GOLPH3 antibody - C-terminal - ab82297 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GOLPH3 antibody - C-terminal (ab82297) at 1/50 dilution + mouse lung tissue lysate at 35 µg

Anti-GOLPH3 Antibody (N-Terminus) IHC-plus™ - LS-B5044 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GOLPH3 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5044 concentration 5 ug/ml.

Anti-GOLPH3 Antibody IHC-plus™ - LS-B10665 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Anti-GOLPH3 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GOLPH3 Antibody - LS-C307728 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GOLPH3 Antibody (aa114-163) - LS-C145732 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GOLPH3 antibody LS-C145732 Western blot of Fetal Liver lysate. Antibody concentration 1 ug/ml.

Anti-GOLPH3 Antibody IHC-plus™ - LS-B10878 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-GOLPH3 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10878 concentration 7.5 ug/ml.

Anti-GOLPH3 Antibody (clone 905CT9.1.1) - LS-C203930 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Mouse
Clonality Monoclonal
Clone 905CT9.1.1
GOLPH3 Antibody western blot of 293,MDA-MB-231 cell line lysates (35 ug/lane). The GOLPH3 antibody detected the GOLPH3 protein (arrow).

Anti-GOLPH3 Antibody (aa251-279) - LS-C100648 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human lung carcinoma with GOLPH3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-GOLPH3 Antibody (aa1-30) - LS-C100647 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with GOLPH3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

GOLPH3 Antibody - NBP1-81804 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GOLPH3 Antibody - NBP1-72134 from Novus Biologicals

Prices $399.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: GOLPH3 Antibody [NBP1-72134] - Staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

GOLPH3 Antibody - NBP1-76241 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: GOLPH3 Antibody [NBP1-76241] - Western blot analysis of GOLPH3 in rat lung tissue lysate with GOLPH3 antibody at (A) 0.5 and (B) 1 ug/mL.

GOLPH3 Antibody - NBP2-16707 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GOLPH3 Antibody [NBP2-16707] - Sample (50 ug of whole cell lysate) A: Mouse Lung, 10% SDS PAGE gel, diluted at 1:3000.

GOLPH3 Antibody - H00064083-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: GOLPH3 Antibody [H00064083-B01P] - Analysis of GOLPH3 expression in transfected 293T cell line by GOLPH3 polyclonal antibody. Lane 1: GOLPH3 transfected lysate(32.78 KDa). Lane 2: Non-transfected lysate.

GOLPH3 Polyclonal Antibody - bs-13488R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GOLPH3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13488R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GOLPH3 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13488R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GOLPH3 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13488R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GOLPH3 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13488R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GOLPH3 Polyclonal Antibody, Cy3 Conjugated - bs-13488R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GOLPH3 Polyclonal Antibody, Cy5 Conjugated - bs-13488R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GOLPH3 Polyclonal Antibody, Cy5.5 Conjugated - bs-13488R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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