GOLPH3

Gene Symbol GOLPH3
Entrez Gene 64083
Alt Symbol GOPP1, GPP34, MIDAS, Vps74
Species Human
Gene Type protein-coding
Description golgi phosphoprotein 3 (coat-protein)
Other Description Golgi phosphoprotein 3|coat protein GPP34|coat-protein|golgi peripheral membrane protein 1, 34 kDa|golgi protein|golgi-associated protein|mitochondrial DNA absence factor
Swissprots Q9UIW5 Q9H4A6
Accessions CAF86422 CCQ43682 EAX10780 EAX10781 EAX10782 Q9H4A6 AJ296152 CAC13124 AK057544 BAG51933 AK075077 BAG52061 AK075156 BAC11438 AK092604 BAG52580 AK128510 BAG54686 AK293368 BAG56882 AK301588 BAG63078 AL133078 CAB61398 BC012123 AAH12123 BC033725 AAH33725 BC063586 AAH63586 NM_022130 NP_071413
Function Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Has also been involved in the control of the localization of Golgi enzymes through interaction with their cytoplasmic part. May play an indirect role in cell migration. Has also been involved in the modulation of mTOR signaling. May also be involved in the regulation of mitochondrial lipids biosynthesis. {ECO:0000269|PubMed:16263763, ECO:0000269|PubMed:19553991, ECO:0000269|PubMed:19837035, ECO:0000269|PubMed:22745132, ECO:0000269|PubMed:23027862, ECO:0000269|PubMed:23345592, ECO:0000269|PubMed:23500462}.
Subcellular Location Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion intermembrane space. Cell membrane {ECO:0000250}. Endosome {ECO:0000250}. Note=Phosphatidylinositol 4-phosphate-binding and oligomerization participate in the recruitment onto Golgi membranes. {ECO:0000305}.
Tissue Specificity Detected in muscle fibers of patients with mitochondrial diseases; not detected in normal muscle fibers.
Top Pathways Transcriptional misregulation in cancer

Golgi phosphoprotein 3 (GOLPH3), Human, ELISA Kit - CSB-EL009668HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Golgi phosphoprotein 3, ELISA Kit - MBS281574 from MyBioSource

Category ELISA Kit
Prices $425.00, $720.00, $3,160.00, $6,055.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.078 ng/mL (mean of 6 independent assays).
Range 0.156 ng/mL - 10 ng/mL.

golgi phosphoprotein 3 (coat-protein) , ELISA Kit - MBS916579 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of human GOLPH3 is typically less than 8.6 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 34.37 pg/ml -2200 pg/ml.

Human Golgi phosphoprotein 3(GOLPH3) ELISA kit - CSB-EL009668HU from Cusabio

Category ELISA Kit
Sensitivity 8.6 pg/ml
Range 34.37 pg/ml-2200 pg/ml

Human Golgi phosphoprotein 3 (GOLPH3) ELISA Kit - EKC33885 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 8.6 pg/ml
Range 34.37 pg/ml-2200 pg/ml

Human GOLPH3 ELISA Kit - E017278 from Biobool

Category ELISA Kit
Sensitivity The minimum detectable dose of human GOLPH3 is typically less than 8.6 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mea

Human Golgi phosphoprotein 3 ELISA Kit - EK3275 from Signalway Antibody

Category ELISA Kit
Prices $599.00
Sizes 1x96t
Range 0.156-10 ng/mL

anti-GOLPH3 antibody - ARG55054 from Arigo Biolaboratories

Category ELISA Kit

anti-GOLPH3 antibody - ARG55094 from Arigo Biolaboratories

Category ELISA Kit

anti-GOLPH3 antibody - ARG55093 from Arigo Biolaboratories

Category ELISA Kit

GOLPH3 ELISA Kit (Human) (OKCA01263) - OKCA01263 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 8.6 pg/mL
Range 34.37 - 2,200 pg/mL

Golgi phosphoprotein 3, ELISA Kit - MBS9427109 from MyBioSource

Category ELISA Kit
Prices $555.00
Sizes 96 tests
Range 0.156-10 ng/mL
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