Gene Symbol | HOOK3 |
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Entrez Gene | 84376 |
Alt Symbol | HK3 |
Species | Human |
Gene Type | protein-coding |
Description | hook microtubule-tethering protein 3 |
Other Description | h-hook3|hHK3|hook homolog 3|protein Hook homolog 3 |
Swissprots | Q9BY13 Q8NBH0 Q86VS8 D3DSY8 |
Accessions | EAW63196 EAW63197 EAW63198 EAW63199 EAW63200 Q86VS8 AK055620 AK090540 BAC03473 AK309224 BC012030 BC013679 BC023658 BC048304 AAH48304 BC056146 AAH56146 BM716064 NM_032410 NP_115786 |
Function | Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex. {ECO:0000250, ECO:0000269|PubMed:11238449, ECO:0000269|PubMed:17237231, ECO:0000269|PubMed:18799622}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11238449}. Golgi apparatus {ECO:0000269|PubMed:11238449}. Note=Enriched at the cis-face of the Golgi complex. Localizes to microtubule asters in prophase. {ECO:0000250}. |
Human HOOK3 full length protein - ab164584 from Abcam
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Human HOOK3 protein fragment - ab164585 from Abcam
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HK3 / Hexokinase 3 Antibody Blocking Peptide - LS-E9523 from LifeSpan Bioscience
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HK3 / Hexokinase 3 Antibody Blocking Peptide - LS-E9524 from LifeSpan Bioscience
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HOOK3 Antibody Blocking Peptide - LS-E23894 from LifeSpan Bioscience
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HOOK3 Antibody Blocking Peptide - LS-E23895 from LifeSpan Bioscience
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Recombinant Human HOOK3 Protein - H00084376-Q01 from Novus Biologicals
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Hexokinase Type III Recombinant Protein - H00003101-P01 from Novus Biologicals
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Hexokinase Type III Partial Recombinant Protein - H00003101-Q01 from Novus Biologicals
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Recombinant Human HOOK3 Protein - H00084376-P01 from Novus Biologicals
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Recombinant Human Hexokinase Type III Protein - NBC1-18387 from Novus Biologicals
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Hexokinase Type III Peptide - P3156 from Novus Biologicals
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Hexokinase Type III Peptide - P3155 from Novus Biologicals
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HOOK3-Antibody-Center-Blocking-Peptide - BP13225c from Abgent, a WuXi AppTec company
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Human HK3 His GST tag protein - orb84582 from Biorbyt
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HOOK3 - H00084376-P01-10 from Acris Antibodies
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HOOK3 - H00084376-P01-25 from Acris Antibodies
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HOOK3 - H00084376-Q01-10 from Acris Antibodies
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HOOK3 - H00084376-Q01-25 from Acris Antibodies
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HOOK3 fusion protein - ag7724 from Proteintech Group
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Hexokinase 3 - HAF-159 from Reagent Proteins
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Recombinant Human Protein Hook homolog 3(HOOK3) - CSB-YP769790HU CSB-EP769790HU CSB-BP769790HU CSB-MP769790HU from Cusabio
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HOOK3 - TP308912 from Acris Antibodies
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HOOK3 Recombinant Protein Antigen - NBP1-81743PEP from Novus Biologicals
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Hexokinase Type III Recombinant Protein Antigen - NBP2-38799PEP from Novus Biologicals
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