HOOK3

Gene Symbol HOOK3
Entrez Gene 84376
Alt Symbol HK3
Species Human
Gene Type protein-coding
Description hook microtubule-tethering protein 3
Other Description h-hook3|hHK3|hook homolog 3|protein Hook homolog 3
Swissprots Q9BY13 Q8NBH0 Q86VS8 D3DSY8
Accessions EAW63196 EAW63197 EAW63198 EAW63199 EAW63200 Q86VS8 AK055620 AK090540 BAC03473 AK309224 BC012030 BC013679 BC023658 BC048304 AAH48304 BC056146 AAH56146 BM716064 NM_032410 NP_115786
Function Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex. {ECO:0000250, ECO:0000269|PubMed:11238449, ECO:0000269|PubMed:17237231, ECO:0000269|PubMed:18799622}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11238449}. Golgi apparatus {ECO:0000269|PubMed:11238449}. Note=Enriched at the cis-face of the Golgi complex. Localizes to microtubule asters in prophase. {ECO:0000250}.

HOOK3 CRISPR/Cas9 KO Plasmid (h) - sc-413639 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK3 HDR Plasmid (h) - sc-413639-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK3 Double Nickase Plasmid (h) - sc-413639-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK3 Double Nickase Plasmid (h2) - sc-413639-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK3 CRISPR Activation Plasmid (h) - sc-413639-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK3 CRISPR Activation Plasmid (h2) - sc-413639-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK3 Lentiviral Activation Particles (h) - sc-413639-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK3 Lentiviral Activation Particles (h2) - sc-413639-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK3 siRNA (h) - sc-60800 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HOOK3 shRNA Plasmid (h) - sc-60800-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HOOK3 shRNA (h) Lentiviral Particles - sc-60800-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Hexokinase Type III RNAi - H00003101-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU023461 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10223 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10223 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09104 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09104

HOOK3 siRNA (Human) - CRJ3463 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HOOK3 - MBS8217597 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HOOK3 shRNA Plasmid (Human) - CHJ3463 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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