HOOK3

Gene Symbol HOOK3
Entrez Gene 84376
Alt Symbol HK3
Species Human
Gene Type protein-coding
Description hook microtubule-tethering protein 3
Other Description h-hook3|hHK3|hook homolog 3|protein Hook homolog 3
Swissprots Q9BY13 Q8NBH0 Q86VS8 D3DSY8
Accessions EAW63196 EAW63197 EAW63198 EAW63199 EAW63200 Q86VS8 AK055620 AK090540 BAC03473 AK309224 BC012030 BC013679 BC023658 BC048304 AAH48304 BC056146 AAH56146 BM716064 NM_032410 NP_115786
Function Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex. {ECO:0000250, ECO:0000269|PubMed:11238449, ECO:0000269|PubMed:17237231, ECO:0000269|PubMed:18799622}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11238449}. Golgi apparatus {ECO:0000269|PubMed:11238449}. Note=Enriched at the cis-face of the Golgi complex. Localizes to microtubule asters in prophase. {ECO:0000250}.

HOOK3 (C-10) - sc-398924 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HOOK3 (C-10): sc-398924. Western blot analysis of HOOK3 expression in HeLa (A), Hep G2 (B) and RT-4 (C) whole cell lysates.

HOOK3 (C-20) - sc-49981 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

HOOK3 (E-20) - sc-49982 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

HOOK3 (N-20) - sc-49983 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-HOOK3 antibody - ab118091 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-HOOK3 antibody (ab118091) at 1 µg/ml + Recombinant Protein at 0.1 µgdeveloped using the ECL technique

Anti-HOOK3 antibody - ab173388 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-HOOK3 antibody (ab173388) at 1 µg/mlLane 1 : HOOK3 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat anti-Mouse IgG at 1/2500 dilution

Anti-HOOK3 antibody - ab133806 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-HOOK3 antibody (ab133806) at 1 µg/ml + Human fetal kidney lysate at 10 µg

Anti-HOOK3 antibody - C-terminal - ab199893 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-HOOK3 antibody - C-terminal (ab199893) at 1/1000 dilutionLane 1 : Mouse thymus total cell extractsLane 2 : HeLa total cell extractsLane 3 : Jurkat total cell extracts

Anti-HOOK3 Antibody - LS-C308282 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-HOOK3 Antibody (aa643-692) - LS-C152036 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HOOK3 antibody Western Blot of Fetal Heart.

Anti-HOOK3 Antibody (aa497-546) - LS-C152037 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HOOK3 antibody Western Blot of Fetal Kidney.

Anti-HOOK3 Antibody (clone 3A5) - LS-C134111 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3A5
Immunoperoxidase of monoclonal antibody to HOOK3 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]

HOOK3 Antibody - NBP1-81743 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HOOK3 Antibody [NBP1-81743] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

HOOK3 Antibody (3A5) - H00084376-M04 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3A5
Western Blot: HOOK3 Antibody (3A5) [H00084376-M04] - Analysis of HOOK3 expression in transfected 293T cell line by HOOK3 monoclonal antibody (M04), clone 3A5. Lane 1: HOOK3 transfected lysate (Predicted MW: 83.1 KDa). Lane 2: Non-transfected lysate.

HOOK3 Antibody - H00084376-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: HOOK3 Antibody [H00084376-B01] - analysis of HOOK3 expression in transfected 293T cell line by HOOK3 MaxPab polyclonal antibody. Lane 1: HOOK3 transfected lysate (83.10 KDa). Lane 2: Non-transfected lysate.

HOOK3 Antibody - H00084376-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: HOOK3 Antibody [H00084376-B01P] - Analysis of HOOK3 expression in transfected 293T cell line by HOOK3 polyclonal antibody. Lane 1: HOOK3 transfected lysate(83.10 KDa). Lane 2: Non-transfected lysate.

Monoclonal Anti-HOOK3 antibody produced in mouse - SAB1401891 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3A5
<B>Immunoblotting</B><BR/>Monoclonal Anti-HOOK3, antibody produced in mouse, clone 3A5, purified immunoglobulin: <B>Cat. No. SAB1401891</B>: Antibody concentration: 1.0 μg/mL. Specific band of ~36.78 kDa using immunogen protein lysate.

Anti-HOOK3 antibody produced in mouse - SAB1401890 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-HOOK3, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1401890</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~83.10 kDa using HOOK3 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-HOOK3 (47-60) antibody produced in rabbit - SAB1103110 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human HOOK3 was separated on SDS-PAGE, blotted with Anti-HOOK3 (47-60) (<B>Cat. No. SAB1103110</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000<BR/>2. Antibody dilution 1:1,000 + HOOK3 immunizing peptide (human, 47-60)

Anti-HOOK3 antibody produced in rabbit - HPA024756 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HOOK3: <B>Cat. No. HPA024756</B>: Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.

HOOK3 Antibody - C-terminal region (ARP65674_P050) - ARP65674_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HOOK3 Antibody - C-terminal region (ARP65675_P050) - ARP65675_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Hexokinase III antibody [4F5] - GTX50057 from GeneTex

Prices $319.00
Sizes 100 μl
Host Mouse
Clonality Monoclonal
Clone 4F5
Anti-Hexokinase 3 antibody [4F5] used in Western blot. GTX50057

KLK3 antibody - 10R-7924 from Fitzgerald

Prices $195.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone AT1D10

HOOK3 antibody - 70R-17787 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
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