Gene Symbol | ATXN1L |
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Entrez Gene | 342371 |
Alt Symbol | BOAT, BOAT1 |
Species | Human |
Gene Type | protein-coding |
Description | ataxin 1-like |
Other Description | ataxin-1-like|brother of ATXN1|brother of ataxin-1 |
Swissprots | P0C7T5 |
Accessions | EAW59221 P0C7T5 AB621810 BAK64146 AI720164 AK025113 AK025339 AL833385 BC042985 BX537575 BX537596 DB097328 NR_024612 NM_001137675 NP_001131147 |
Function | Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1) (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16121196}. Cell projection, dendrite {ECO:0000269|PubMed:16121196}. Note=Forms nuclear foci. Colocalizes with NCOR2 and HDAC3. Distributed beyond the nucleus into the cell body and dendrites in Purkinje cells and in inferior olive cells. |
Tissue Specificity | Expressed in cerebellum and cerebral cortex. {ECO:0000269|PubMed:16121196}. |
ATXN1L (N-12) - sc-163714 from Santa Cruz Biotechnology
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ATXN1L (C-14) - sc-163713 from Santa Cruz Biotechnology
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Anti-ATXN1L antibody - ab138610 from Abcam
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Anti-ATXN1L Antibody (aa384-411, AP) - LS-C252083 from LifeSpan Bioscience
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Anti-ATXN1L Antibody (aa384-411, Biotin) - LS-C252086 from LifeSpan Bioscience
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Anti-ATXN1L Antibody (aa384-411, APC) - LS-C252085 from LifeSpan Bioscience
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Anti-ATXN1L Antibody (aa384-411, FITC) - LS-C252087 from LifeSpan Bioscience
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Anti-ATXN1L Antibody (aa384-411, Azide-free, HRP) - LS-C252088 from LifeSpan Bioscience
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Anti-ATXN1L Antibody (aa384-411, PE) - LS-C252089 from LifeSpan Bioscience
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Anti-ATXN1L Antibody (aa384-411) - LS-C319716 from LifeSpan Bioscience
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Anti-ATXN1L Antibody (aa384-411) - LS-C159143 from LifeSpan Bioscience
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ANTI-ATXN1L (CENTER) antibody produced in rabbit - SAB1305822 from Sigma-Aldrich
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ATXN1L-Antibody-Center - AP18768c from Abgent, a WuXi AppTec company
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Anti -ATXN1L, ID (ATXN1L, BOAT, BOAT1, Ataxin-1-like, Brother of ataxin-1) - 032317 from USBiological Life Science
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Anti -ATXN1L, ID (ATXN1L, BOAT, BOAT1, Ataxin-1-like, Brother of ataxin-1) (AP) - 032317-AP from USBiological Life Science
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Anti -ATXN1L, ID (ATXN1L, BOAT, BOAT1, Ataxin-1-like, Brother of ataxin-1) (APC) - 032317-APC from USBiological Life Science
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Anti -ATXN1L, ID (ATXN1L, BOAT, BOAT1, Ataxin-1-like, Brother of ataxin-1) (Azide free)(HRP) - 032317-HRP from USBiological Life Science
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Anti -ATXN1L, ID (ATXN1L, BOAT, BOAT1, Ataxin-1-like, Brother of ataxin-1) (Biotin) - 032317-Biotin from USBiological Life Science
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Anti -ATXN1L, ID (ATXN1L, BOAT, BOAT1, Ataxin-1-like, Brother of ataxin-1) (FITC) - 032317-FITC from USBiological Life Science
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Anti -ATXN1L, ID (ATXN1L, BOAT, BOAT1, Ataxin-1-like, Brother of ataxin-1) (PE) - 032317-PE from USBiological Life Science
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ATXN1L Antibody - middle region (OAAB14306) - OAAB14306 from Aviva Systems Biology
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ATXN1L Antibody - abx030547 from Abbexa
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ATXN1L antibody (Center) - STJ46963 from St John's Laboratory Ltd
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ATXN1L, Polyclonal Antibody - MBS649838 from MyBioSource
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Anti-ATXN1L (aa 384-411) polyclonal antibody - DPABH-01515 from Creative Diagnostics
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