ATXN1L

Gene Symbol ATXN1L
Entrez Gene 342371
Alt Symbol BOAT, BOAT1
Species Human
Gene Type protein-coding
Description ataxin 1-like
Other Description ataxin-1-like|brother of ATXN1|brother of ataxin-1
Swissprots P0C7T5
Accessions EAW59221 P0C7T5 AB621810 BAK64146 AI720164 AK025113 AK025339 AL833385 BC042985 BX537575 BX537596 DB097328 NR_024612 NM_001137675 NP_001131147
Function Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1) (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:16121196}. Cell projection, dendrite {ECO:0000269|PubMed:16121196}. Note=Forms nuclear foci. Colocalizes with NCOR2 and HDAC3. Distributed beyond the nucleus into the cell body and dendrites in Purkinje cells and in inferior olive cells.
Tissue Specificity Expressed in cerebellum and cerebral cortex. {ECO:0000269|PubMed:16121196}.

ATXN1L CRISPR/Cas9 KO Plasmid (h) - sc-410432 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATXN1L HDR Plasmid (h) - sc-410432-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATXN1L Double Nickase Plasmid (h) - sc-410432-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATXN1L Double Nickase Plasmid (h2) - sc-410432-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATXN1L CRISPR Activation Plasmid (h) - sc-410432-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATXN1L CRISPR Activation Plasmid (h2) - sc-410432-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATXN1L Lentiviral Activation Particles (h) - sc-410432-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATXN1L Lentiviral Activation Particles (h2) - sc-410432-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATXN1L siRNA (h) - sc-93421 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATXN1L shRNA Plasmid (h) - sc-93421-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATXN1L shRNA (h) Lentiviral Particles - sc-93421-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU228951 from Sigma-Aldrich

Category siRNA
Prices $140.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3759 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3759 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ATXN1L siRNA (Human) - CRJ7396 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATXN1L - MBS8202930 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ATXN1L (NM_001137675.3) - SHH243546 from Creative biogene

Category siRNA
Species Reactivities Human

ATXN1L shRNA Plasmid (Human) - CHJ7396 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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