Gene Symbol | TWF2 |
---|---|
Entrez Gene | 11344 |
Alt Symbol | A6RP, A6r, MSTP011, PTK9L |
Species | Human |
Gene Type | protein-coding |
Description | twinfilin actin-binding protein 2 |
Other Description | A6-related protein|PTK9L protein tyrosine kinase 9-like (A6-related protein)|protein tyrosine kinase 9-like (A6-related protein)|twinfilin, actin-binding protein, homolog 2|twinfilin-1-like protein|twinfilin-2 |
Swissprots | Q9Y3F5 Q6IBS0 |
Accessions | EAW65194 Q6IBS0 AF109365 AAQ13513 AL136773 CAB66707 BC000327 AAH00327 BC003161 AAH03161 BC016452 AAH16452 BI551353 CR456732 CAG33013 CR533520 CAG38551 DQ891754 ABM82680 DQ894936 ABM85862 Y17169 CAB38055 NM_007284 NP_009215 |
Function | Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10406962}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:10406962}. Cell projection, stereocilium {ECO:0000250}. Note=Perinuclear and G-actin-rich cortical actin structure sublocalization. |
Tissue Specificity | Ubiquitously expressed (at protein level). {ECO:0000269|PubMed:10406962}. |
Human TWF2 full length protein - ab161423 from Abcam
|
||||||||||
Human TWF2 protein fragment - ab161424 from Abcam
|
||||||||||
TWF2 / PTK9L Antibody Blocking Peptide - LS-E1137 from LifeSpan Bioscience
|
||||||||||
TWF2 / PTK9L Antibody Blocking Peptide - LS-E18814 from LifeSpan Bioscience
|
||||||||||
Recombinant Human TWF2 Protein - H00011344-Q01 from Novus Biologicals
|
||||||||||
Recombinant Human TWF2 Protein - H00011344-P01 from Novus Biologicals
|
||||||||||
PTK9L-Antibody-N-term-Blocking-peptide - BP11665a from Abgent, a WuXi AppTec company
|
||||||||||
Twinfilin-2 (TWF2) - H00011344-P01-10 from Acris Antibodies
|
||||||||||
Twinfilin-2 (TWF2) - H00011344-P01-25 from Acris Antibodies
|
||||||||||
Twinfilin-2 (TWF2) - H00011344-Q01-10 from Acris Antibodies
|
||||||||||
Twinfilin-2 (TWF2) - H00011344-Q01-25 from Acris Antibodies
|
||||||||||
TWF2 fusion protein - ag6553 from Proteintech Group
|
||||||||||
TWF2 fusion protein - Ag6542 from Proteintech Group
|
||||||||||
Recombinant Human TWF2, GST-tagged - TWF2-3493H from Creative Biomart
|
||||||||||
Recombinant Human Twinfilin-2(TWF2) - CSB-YP764224HU CSB-EP764224HU CSB-BP764224HU CSB-MP764224HU from Cusabio
|
||||||||||
Twinfilin-2 (TWF2) - TP301791 from Acris Antibodies
|
||||||||||
TWF2 Recombinant Protein Antigen - NBP2-47591PEP from Novus Biologicals
|
||||||||||
Twinfilin-2-PTK9L-Antibody-C-term-Blocking-peptide - BP7180a from Abgent, a WuXi AppTec company
|
||||||||||
TWF2 Peptide, Human - M34GP16882H from Creative Peptides
|
||||||||||
Human TWF2 protein - orb54266 from Biorbyt
|
||||||||||
PTK9L, Recombinant Protein - MBS515641 from MyBioSource
|
||||||||||
TWF2 Recombinant Protein (Human) (OPCA04753) - OPCA04753 from Aviva Systems Biology
|
||||||||||
Recombinant Human Twinfilin-2 (TWF2) - RPC23248 from Biomatik
|