TWF2

Gene Symbol	TWF2
Entrez Gene	11344
Alt Symbol	A6RP, A6r, MSTP011, PTK9L
Species	Human
Gene Type	protein-coding
Description	twinfilin actin-binding protein 2
Other Description	A6-related protein|PTK9L protein tyrosine kinase 9-like (A6-related protein)|protein tyrosine kinase 9-like (A6-related protein)|twinfilin, actin-binding protein, homolog 2|twinfilin-1-like protein|twinfilin-2
Swissprots	Q9Y3F5 Q6IBS0
Accessions	EAW65194 Q6IBS0 AF109365 AAQ13513 AL136773 CAB66707 BC000327 AAH00327 BC003161 AAH03161 BC016452 AAH16452 BI551353 CR456732 CAG33013 CR533520 CAG38551 DQ891754 ABM82680 DQ894936 ABM85862 Y17169 CAB38055 NM_007284 NP_009215
Function	Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10406962}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:10406962}. Cell projection, stereocilium {ECO:0000250}. Note=Perinuclear and G-actin-rich cortical actin structure sublocalization.
Tissue Specificity	Ubiquitously expressed (at protein level). {ECO:0000269|PubMed:10406962}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Twinfilin-2 CRISPR/Cas9 KO Plasmid (h) - sc-409819 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-2 HDR Plasmid (h) - sc-409819-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-2 Double Nickase Plasmid (h) - sc-409819-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-2 Double Nickase Plasmid (h2) - sc-409819-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-2 CRISPR Activation Plasmid (h) - sc-409819-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-2 CRISPR Activation Plasmid (h2) - sc-409819-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-2 Lentiviral Activation Particles (h) - sc-409819-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-2 Lentiviral Activation Particles (h2) - sc-409819-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Twinfilin-2 siRNA (h) - sc-78430 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Twinfilin-2 shRNA Plasmid (h) - sc-78430-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Twinfilin-2 shRNA (h) Lentiviral Particles - sc-78430-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® siRNA - SIHK2389 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK2388 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK2390 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN22292 from Sigma-Aldrich Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22292 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03872 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr03872

TWF2 siRNA (Human) - CRH7771 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TWF2 RNAi - H00011344-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

TWF2 - MBS8230518 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human TWF2 (NM_007284.3) - SHH438048 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human TWF2(NM_007284.3) - SHL107334 from Creative biogene Category siRNA Species Reactivities Human

Human TWF2 siRNA - orb268273 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TWF2 shRNA Plasmid (Human) - CHH7771 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

TWF2 miRNA 3'UTR clone - MiUTR1H-10888 from Creative biogene Species Reactivities Human

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