MKRN1

Gene Symbol	MKRN1
Entrez Gene	23608
Alt Symbol	RNF61
Species	Human
Gene Type	protein-coding
Description	makorin ring finger protein 1
Other Description	E3 ubiquitin-protein ligase makorin-1|RING finger protein 61
Swissprots	Q9UEZ7 Q59G11 Q9UHC7 Q6GSF1 A4D1T7 B3KXB4 Q256Y7 Q9H0G0 Q9UHW2
Accessions	AAF18979 EAL24026 EAW83949 EAW83950 EAW83951 EAW83952 EAW83953 Q9UHC7 AB209298 BAD92535 AF117233 AAF17214 AF192784 AAF17487 AI828363 AK024987 AK027137 AK127030 BAG54426 AK297361 BAG59808 AK315552 BAG37929 AL136812 CAB66746 AM236048 CAJ84705 BC012398 BC025955 AAH25955 BC037400 AAH37400 BC051821 BC064838 AAH64838 BC127216 AAI27217 CA438497 DC400746 DQ892404 ABM83330 EU176516 ABW03317 XM_011515996 XP_011514298 XM_011515997 XP_011514299 XM_011515998 XP_011514300 NM_001145125 NP_001138597 NM_001291663 NP_001278592 NM_013446 NP_038474 NR_117084
Function	E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. Keeps cells alive by suppressing p53/TP53 under normal conditions, but stimulates apoptosis by repressing CDKN1A under stress conditions. Acts as a negative regulator of telomerase. Has negative and positive effects on RNA polymerase II-dependent transcription. {ECO:0000269|PubMed:16785614, ECO:0000269|PubMed:19536131}.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:10843807, ECO:0000269|PubMed:16785614}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MKRN1 full length protein - ab161710 from Abcam Category Protein Source Wheat germ Species Human

Human MKRN1 protein fragment - ab161711 from Abcam Category Protein Source Wheat germ Species Human

MKRN1 peptide (195-209) - ab45735 from Abcam Category Peptide Species Human

MKRN1 Antibody Blocking Peptide - LS-E27676 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MKRN1 Antibody Blocking Peptide - LS-E15825 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MKRN1 Antibody Blocking Peptide - LS-E15884 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MKRN1 Protein - H00023608-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human MKRN1 Protein - H00023608-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MKRN1 Blocking Peptide - 33R-8272 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MKRN1 Blocking Peptide - 33R-3207 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MKRN1 Peptide - AC21-2492-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

MKRN1 Peptide - AC21-2802-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Makorin-1 - H00023608-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Makorin-1 - H00023608-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Makorin-1 - H00023608-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MKRN1 Peptide - 42-850P from ProSci Category Peptide Species Human

MKRN1 fusion protein - Ag3465 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human MKRN1, GST-tagged - MKRN1-895H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human E3 ubiquitin-protein ligase makorin-1(MKRN1) - CSB-YP883390HU CSB-EP883390HU CSB-BP883390HU CSB-MP883390HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Makorin-1 (transcript variant 1) - TP306848 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Makorin, Peptide - MBS428161 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Dog

MKRN1, Peptide - MBS427401 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Dog, Pig, Bovine

MKRN1 Protein - NBP1-87123PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

MKRN1-Blocking-PeptideCenter - BP19708c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MKRN1 Peptide, Human - M34GP09548H from Creative Peptides Category Peptide Source Synthetic. Species Human

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