OTUD5

Gene Symbol OTUD5
Entrez Gene 55593
Alt Symbol DUBA
Species Human
Gene Type protein-coding
Description OTU deubiquitinase 5
Other Description OTU domain containing 5|OTU domain-containing protein 5|deubiquinating enzyme A|deubiquitinating enzyme A
Swissprots B4DGG7 Q4KMN9 G5E9D7 Q9H650 Q96G74 Q9NT65 Q9H9U0 Q8N6T5
Accessions EAW50722 EAW50723 EAW50724 EAW50725 EAW50726 EAW50727 Q96G74 AK022612 BAB14131 AK026260 BAB15416 AK294590 BAG57778 AL137509 CAB70778 BC009917 AAH09917 BC011738 BC028225 AAH28225 BC098440 AAH98440 BM797460 BY799160 CB243128 CN368451 DA237046 DC419901 XM_005272622 XP_005272679 XM_005278039 XP_005278096 XM_005278042 XP_005278099 XM_006724537 XP_006724600 XM_011543932 XP_011542234 XM_011543933 XP_011542235 XM_011543934 XP_011542236 NM_001136157 NP_001129629 NM_001136158 NP_001129630 NM_001136159 NP_001129631 NM_017602 NP_060072
Function Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'- linked ubiquitin chains (in vitro). {ECO:0000269|PubMed:17991829, ECO:0000269|PubMed:22245969, ECO:0000269|PubMed:23827681}.
Tissue Specificity Expressed in various tissues, including the liver and placenta, as well as in peripheral blood leukocytes. {ECO:0000269|PubMed:17991829}.
Top Pathways RIG-I-like receptor signaling pathway

OTUD5 CRISPR/Cas9 KO Plasmid (h) - sc-412550 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUD5 HDR Plasmid (h) - sc-412550-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUD5 Double Nickase Plasmid (h) - sc-412550-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUD5 Double Nickase Plasmid (h2) - sc-412550-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUD5 CRISPR Activation Plasmid (h) - sc-412550-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUD5 CRISPR Activation Plasmid (h2) - sc-412550-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUD5 Lentiviral Activation Particles (h) - sc-412550-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUD5 Lentiviral Activation Particles (h2) - sc-412550-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OTUD5 siRNA (h) - sc-91274 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OTUD5 shRNA Plasmid (h) - sc-91274-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OTUD5 shRNA (h) Lentiviral Particles - sc-91274-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU045011 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16199 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16199 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

OTUD5 siRNA (Human) - CRJ0758 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human OTUD5 (NM_017602.3) - SHH369136 from Creative biogene

Category siRNA
Species Reactivities Human

OTUD5 shRNA Plasmid (Human) - CHJ0758 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

OTUD5 miRNA 3'UTR clone - MiUTR3H-02917 from Creative biogene

Species Reactivities Human

OTUD5 miRNA 3'UTR clone - MiUTR3H-02918 from Creative biogene

Species Reactivities Human

OTUD5 miRNA 3'UTR clone - MiUTR3H-02919 from Creative biogene

Species Reactivities Human

OTUD5 miRNA 3'UTR clone - MiUTR3H-02920 from Creative biogene

Species Reactivities Human
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