KCNA5

Gene Symbol	KCNA5
Entrez Gene	3741
Alt Symbol	ATFB7, HCK1, HK2, HPCN1, KV1.5, PCN1
Species	Human
Gene Type	protein-coding
Description	potassium channel, voltage gated shaker related subfamily A, member 5
Other Description	cardiac potassium channel|insulinoma and islet potassium channel|potassium channel 1|potassium voltage-gated channel subfamily A member 5|potassium voltage-gated channel, shaker-related subfamily, member 5|voltage-gated potassium channel HK2|voltage-gated potassium channel protein Kv1.5|voltage-gated potassium channel subunit Kv1.5
Swissprots	Q4KKT8 Q9UDA4 Q4VAJ1 P22460 Q4VAJ2
Accessions	EAW88830 P22460 BC096357 AAH96357 BC096358 AAH96358 BC099665 AAH99665 BC099666 AAH99666 BM663787 BM692565 M55513 AAA36422 M60451 AAA61276 M83254 AAA60146 NM_002234 NP_002225
Function	Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel (PubMed:12130714). Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation (PubMed:12130714). Homotetrameric channels display rapid activation and slow inactivation (PubMed:8505626, PubMed:12130714). May play a role in regulating the secretion of insulin in normal pancreatic is
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12130714, ECO:0000269|PubMed:8505626}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity	Pancreatic islets and insulinoma.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

KV1.5 (A-3) - sc-377110 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

KV1.5 (E-20) - sc-11675 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

KV1.5 (H-120) - sc-25681 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

KV1.5 (N-16) - sc-11671 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

KV1.5 (P-15) - sc-11672 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-KCNA5 antibody - ab181798 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KCNA5 antibody - ab110469 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KCNA5 antibody - ab101788 from Abcam Host Rabbit Clonality Polyclonal

Anti-KCNA5 antibody - ab65791 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KCNA5 antibody [2D10.D6] - ab184691 from Abcam Prices $370.00 Sizes 50 µl Host Mouse Clonality Monoclonal Clone 2D10.D6

Anti-KCNA5 / Kv1.5 Antibody (C-Terminus) - LS-C8392 from LifeSpan Bioscience Prices $375.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-KCNA5 / Kv1.5 Antibody (C-Terminus) - LS-C153510 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KCNA5 / Kv1.5 Antibody (aa508-536, AP) - LS-C215356 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KCNA5 / Kv1.5 Antibody (aa508-536, APC) - LS-C215359 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KCNA5 / Kv1.5 Antibody (aa508-536, Biotin) - LS-C215360 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KCNA5 / Kv1.5 Antibody (aa508-536, Azide-free, HRP) - LS-C215362 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KCNA5 / Kv1.5 Antibody (aa508-536, FITC) - LS-C215361 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KCNA5 / Kv1.5 Antibody (aa508-536, PE) - LS-C215364 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KCNA5 / Kv1.5 Antibody (aa542-602, clone S7-45, Atto 655) - LS-C227894 from LifeSpan Bioscience Host Mouse Clonality Monoclonal Clone S7-45

Anti-KCNA5 / Kv1.5 Antibody (aa72-121) - LS-C134976 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-KCNA5 / Kv1.5 Antibody (aa542-602, clone S7-45, Atto 680) - LS-C227895 from LifeSpan Bioscience Host Mouse Clonality Monoclonal Clone S7-45

Anti-KCNA5 / Kv1.5 Antibody (aa542-602, clone S7-45, Atto 700) - LS-C227898 from LifeSpan Bioscience Host Mouse Clonality Monoclonal Clone S7-45

Anti-KCNA5 / Kv1.5 Antibody (aa542-602, clone S7-45, Atto 633) - LS-C227896 from LifeSpan Bioscience Host Mouse Clonality Monoclonal Clone S7-45

Anti-KCNA5 / Kv1.5 Antibody - LS-C26740 from LifeSpan Bioscience Prices $330.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KCNA5 / Kv1.5 Antibody (aa542-602, clone S7-45, AP) - LS-C227899 from LifeSpan Bioscience Host Mouse Clonality Monoclonal Clone S7-45

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