KCNA5

Gene Symbol	KCNA5
Entrez Gene	3741
Alt Symbol	ATFB7, HCK1, HK2, HPCN1, KV1.5, PCN1
Species	Human
Gene Type	protein-coding
Description	potassium channel, voltage gated shaker related subfamily A, member 5
Other Description	cardiac potassium channel|insulinoma and islet potassium channel|potassium channel 1|potassium voltage-gated channel subfamily A member 5|potassium voltage-gated channel, shaker-related subfamily, member 5|voltage-gated potassium channel HK2|voltage-gated potassium channel protein Kv1.5|voltage-gated potassium channel subunit Kv1.5
Swissprots	Q4KKT8 Q9UDA4 Q4VAJ1 P22460 Q4VAJ2
Accessions	EAW88830 P22460 BC096357 AAH96357 BC096358 AAH96358 BC099665 AAH99665 BC099666 AAH99666 BM663787 BM692565 M55513 AAA36422 M60451 AAA61276 M83254 AAA60146 NM_002234 NP_002225
Function	Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel (PubMed:12130714). Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation (PubMed:12130714). Homotetrameric channels display rapid activation and slow inactivation (PubMed:8505626, PubMed:12130714). May play a role in regulating the secretion of insulin in normal pancreatic is
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12130714, ECO:0000269|PubMed:8505626}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity	Pancreatic islets and insulinoma.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HK2 / Hexokinase 2 Antibody Blocking Peptide - LS-E19535 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HK2 / Hexokinase 2 Antibody Blocking Peptide - LS-E19536 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HK2 / Hexokinase 2 Antibody Blocking Peptide - LS-E9525 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HK2 / Hexokinase 2 Antibody Blocking Peptide - LS-E9526 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KCNA5 / Kv1.5 Antibody Blocking Peptide - LS-E4677 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KCNA5 / Kv1.5 Antibody Blocking Peptide - LS-E12020 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Hexokinase 2 Protein - NBC1-18389 from Novus Biologicals Category Protein Prices $499.00 Sizes 100 µg Source E.coli Species Human

Recombinant Human Hexokinase 2 Protein - H00003099-P01 from Novus Biologicals Category Protein Prices $529.00 Sizes 25 µg Source Wheat Germ Species Human

Hexokinase 2 Partial Recombinant Protein - H00003099-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

Hexokinase 2 Recombinant Protein - P3457 from Novus Biologicals Category Protein Prices $1,049.00 Sizes 100 µg Species Human

Hexokinase 2 Peptide - P3159 from Novus Biologicals Category Peptide Species Human

Hexokinase 2 Peptide - P3158 from Novus Biologicals Category Peptide Species Human

KCNA5-Antibody-C-term-Blocking-Peptide - BP17043b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KCNA5 Blocking Peptide - 33R-2102 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Kv1.5 Blocking Peptide - abx062837 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Dog, Pig

KCNA5 fusion protein - Ag16397 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human KCNA5, GST-tagged - KCNA5-230H from Creative Biomart Category Protein Source E.coli Species Human

Hexokinase 2 - HAF-161 from Reagent Proteins Category Protein Prices $679.00, $1,519.00 Sizes 100.00 µg, 500 µg Source E.coli Species Human

Kv1.5 Blocking Peptide - CBP1643 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Dog, Pig

Kv1.5 Peptide - BS5778P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

KCNA5 Protein - abx163722 from Abbexa Category Protein Species Human

KCNA5 Protein - abx163380 from Abbexa Category Protein Species Human, Mouse, Rat

Potassium voltage-gated channel subfamily A member 5 (KCNA5), Recombinant Protein - MBS953354 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Hexokinase 2 Protein - NBP1-90922PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

Kv1.5 Recombinant Protein Antigen - NBP2-33891PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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