PPM1D

Gene Symbol	PPM1D
Entrez Gene	8493
Alt Symbol	PP2C-DELTA, WIP1
Species	Human
Gene Type	protein-coding
Description	protein phosphatase, Mg2+/Mn2+ dependent, 1D
Other Description	protein phosphatase 1D|protein phosphatase 1D magnesium-dependent, delta isoform|protein phosphatase 2C delta isoform|protein phosphatase Wip1|wild-type p53-induced phosphatase 1
Swissprots	Q53XP4 O15297 Q8IVR6 Q6P991
Accessions	EAW51408 EAW51409 O15297 AA326266 AK054573 AK299773 BAG61656 AK312902 BAG35748 AU280469 BC016480 AAH16480 BC032826 BC033893 AAH33893 BC042418 AAH42418 BC060877 AAH60877 BT009780 AAP88782 BU616782 DQ891047 ABM81973 EU176552 ABW03353 U78305 AAB61637 XR_934577 NM_003620 NP_003611
Function	Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins. {ECO:0000269|PubMed:15870257, ECO:0000269|PubMed:16311512}.
Top Pathways	p53 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PPM1D peptide - ab32657 from Abcam Category Peptide

Human PPM1D protein fragment - ab160051 from Abcam Category Protein Source Wheat germ Species Human

Human PPM1D protein fragment - ab202182 from Abcam Category Protein Source E. coli Species Human

PPM1D / WIP1 Antibody Blocking Peptide - LS-E2777 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PPM1D / WIP1 Antibody Blocking Peptide - LS-E9579 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PPM1D Partial Recombinant Protein - H00008493-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

PPM1D Peptide - P3271 from Novus Biologicals Category Peptide Species Human

PPM1D-Antibody-Center-Blocking-peptide - BP13875c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PPM1D-Antibody-C-term-Blocking-Peptide - BP8437b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PPM1D protein (His tag) - 80R-4126 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source E.coli

PPM1D (98-375, His-tag) - AR51812PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

PPM1D (98-375, His-tag) - AR51812PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

Protein phosphatase 1D / PPM1D - H00008493-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

Protein phosphatase 1D / PPM1D - H00008493-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Protein phosphatase 1D / PPM1D - H00008493-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PPM1D Peptide - 8043P from ProSci Category Peptide Species Human

Recombinant Human Protein phosphatase 1D(PPM1D) - CSB-YP018491HU CSB-EP018491HU CSB-BP018491HU CSB-MP018491HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PPM1D, 98-375aa, Human, His tag, E.coli (Denatured) - ATGP2992 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 10 µg, 50 µg, 250 µg Species Human

PPM1D fusion protein - Ag24761 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Protein phosphatase 1D / PPM1D - TP309328 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

PPM1D, Recombinant Protein - MBS205875 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 50 µg, 250 µg Source E Coli Species Human

PPM1D Recombinant Protein Antigen - NBP1-87249PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PPM1D-Antibody-N-term-Blocking-Peptide - BP8468a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PPM1D Peptide, Human - M34GP12214H from Creative Peptides Category Peptide Source Synthetic. Species Human

PPM1D Recombinant Protein - NBP2-51998 from Novus Biologicals Category Protein Prices $259.00 Sizes 50 µg Source E. coli Species Human

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