PPM1D

Gene Symbol PPM1D
Entrez Gene 8493
Alt Symbol PP2C-DELTA, WIP1
Species Human
Gene Type protein-coding
Description protein phosphatase, Mg2+/Mn2+ dependent, 1D
Other Description protein phosphatase 1D|protein phosphatase 1D magnesium-dependent, delta isoform|protein phosphatase 2C delta isoform|protein phosphatase Wip1|wild-type p53-induced phosphatase 1
Swissprots Q53XP4 O15297 Q8IVR6 Q6P991
Accessions EAW51408 EAW51409 O15297 AA326266 AK054573 AK299773 BAG61656 AK312902 BAG35748 AU280469 BC016480 AAH16480 BC032826 BC033893 AAH33893 BC042418 AAH42418 BC060877 AAH60877 BT009780 AAP88782 BU616782 DQ891047 ABM81973 EU176552 ABW03353 U78305 AAB61637 XR_934577 NM_003620 NP_003611
Function Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins. {ECO:0000269|PubMed:15870257, ECO:0000269|PubMed:16311512}.
Top Pathways p53 signaling pathway

WIP1 (D4F7) Rabbit mAb - 11901 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4F7
Western blot analysis of extracts from various cell lines using WIP1 (D4F7) Rabbit mAb.

Wip1 (C-18) - sc-69130 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Wip1 (F-10) - sc-376257 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Wip1 (F-10): sc-376257. Western blot analysis of Wip1 expression in non-transfected: sc-110760 (A) and human Wip1 transfected: sc-113282 (B) 293 whole cell lysates.

Wip1 (H-300) - sc-20712 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Wip1 (H-300): sc-20712. Western blot analysis of Wip1 expression in F9 whole cell lysate

Wip1 (P-14) - sc-69131 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PPM1D antibody - ab31270 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PPM1D antibody (ab31270) at 1 µg/mlLane 1 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate Lane 2 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-PPM1D antibody - ab37495 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PPM1D antibody (ab37495) + 293 cell lysate

Anti-PPM1D antibody - ab56332 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-PPM1D antibody (ab56332) at 5 µg/ml + 0.2 µg/lane of partial recombinant protein with a tagSecondaryGoat anti mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

Anti-PPM1D antibody [2804D1a] - ab72000 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2804D1a
Anti-PPM1D antibody [2804D1a] (ab72000) + immunising recombinant protein

Anti-PPM1D / WIP1 Antibody (aa183-212, PE) - LS-C216919 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPM1D / WIP1 Antibody (aa183-212, Azide-free, HRP) - LS-C216920 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPM1D / WIP1 Antibody (aa183-212, FITC) - LS-C216918 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPM1D / WIP1 Antibody (C-Terminus, AP) - LS-C220463 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPM1D / WIP1 Antibody (aa571-602) - LS-C101018 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
The anti-PPM1D antibody is used in Western blot to detect PPM1D in 293 cell lysate.

Anti-PPM1D / WIP1 Antibody (C-Terminus, APC) - LS-C220464 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPM1D / WIP1 Antibody (C-Terminus, FITC) - LS-C220466 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPM1D / WIP1 Antibody (C-Terminus, Biotin) - LS-C220465 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPM1D / WIP1 Antibody (C-Terminus, Azide-free, HRP) - LS-C220467 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPM1D / WIP1 Antibody (C-Terminus, PE) - LS-C220468 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPM1D / WIP1 Antibody (aa500-550) - LS-C287535 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PPM1D / WIP1 Antibody (aa182-212) - LS-C324225 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPM1D / WIP1 Antibody (C-Terminus) - LS-C328370 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPM1D / WIP1 Antibody - LS-C341965 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PPM1D / WIP1 Antibody (clone 2804D1a) - LS-C342713 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2804D1a
Left : Western blot analysis of immunized recombinant protein, using anti-PPM1D monoclonal antibody. Right : CBB staining of immunized recombinant protein.

Anti-PPM1D / WIP1 Antibody - LS-C334560 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using PPM1D antibody.
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