JAM3

Gene Symbol	JAM3
Entrez Gene	83700
Alt Symbol	JAM-2, JAM-3, JAM-C, JAMC
Species	Human
Gene Type	protein-coding
Description	junctional adhesion molecule 3
Other Description	junctional adhesion molecule C
Swissprots	Q96FL1 Q8WWL8 B3KWG9 Q9BX67
Accessions	CAF85939 CAF86920 CBX47566 CCA65346 EAW67817 EAW67818 EAW67819 EAW67820 Q9BX67 AF356518 AAK27221 AF448478 AAM20925 AJ344431 CAC69845 AJ416101 CAC94776 AK027435 AK074769 BAC11195 AK075309 BAC11538 AK125071 BAG54131 AK225666 AY358335 AAQ88701 BC010690 AAH10690 BC012147 AAH12147 BC057284 BC063031 W76344 NM_001205329 NP_001192258 NM_032801 NP_116190
Function	Participates in cell-cell adhesion. It is a counter- receptor for ITGAM, mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN). The soluble form is a mediator of angiogenesis. {ECO:0000269|PubMed:12208882, ECO:0000269|PubMed:15194813, ECO:0000269|PubMed:20592283}.
Subcellular Location	Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cell junction, desmosome. Secreted, extracellular space. Note=In epithelial cells, it is expressed at desmosomes but not at tight junctions. Localizes at the cell surface of endothelial cells; treatment of endothelial cells with vascular endothelial growth factor stimulates recruitment of JAM3 to cell-cell contacts.
Tissue Specificity	Highest expression in placenta, brain and kidney. Significant expression is detected on platelets. Expressed in intestinal mucosa cells. Expressed in the vascular endothelium. Found in serum (at protein level). Also detected in the synovial fluid of patients with rheumatoid arthritis, psoriatic arthritis or ostearthritis (at protein level). {ECO:0000269|PubMed:11590146, ECO:0000269|PubMed:11944976, ECO:0000269|PubMed:12208882, ECO:0000269|PubMed:15194813, ECO:0000269|PubMed:15994945, ECO:0000269|PubMed:20592283}.
Top Pathways	Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human JAM3 ELISA Kit (Sandwich ELISA) - LS-F7999 from LifeSpan Bioscience Category ELISA Kit Prices $790.00 Sizes 1 plate Sensitivity 15.63 pg/ml Range 15.63-1000 pg/ml

Human JAM3 ELISA Kit - abx152075 from Abbexa Category ELISA Kit Sensitivity 6.5 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Junctional Adhesion Molecule 3 (JAM3), Human, ELISA Kit - SEL637Hu from ARP American Research Products Category ELISA Kit Prices $790.00 Sizes 96 t Sensitivity 0.058ng/mL Range 0.156-10ng/mL

Junctional adhesion molecule C (JAM3), Human, ELISA Kit - CSB-EL011937HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 9.75 pg/ml Range 39 pg/ml-2500 pg/ml

Custom Human JAM-C ELISA - ELH-JAMC from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

junctional adhesion molecule 3, ELISA Kit - MBS920073 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.75 pg/ml Range 39 pg/ml-2500 pg/ml

Junctional Adhesion Molecule 3 (JAM3), ELISA Kit - MBS2020887 from MyBioSource Category ELISA Kit Prices $410.00, $610.00, $830.00, $3,420.00, $6,200.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 6.5pg/mL. Range 15.63-1000pg/mL

ELISA Kit for Junctional Adhesion Molecule 3 (JAM3) - SEL637Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 6.5pg/mL. Range 15.63-1000pg/mL The standard curve concentrations used for the ELISA’s were 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL, 15.63pg/mL

Human Junctional adhesion molecule C(JAM3) ELISA kit - CSB-EL011937HU from Cusabio Category ELISA Kit Sensitivity 9.75 pg/ml Range 39 pg/ml-2500 pg/ml

ELISA Kit for Junctional Adhesion Molecule 3 (JAM3) - SEL637Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 6.5pg/mL. Range 15.625-1000pg/mL The standard curve concentrations used for the ELISA's were 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL, 15.625pg/mL

Human Junctional Adhesion Molecule 3 (JAM3) ELISA Kit - EKU05423 from Biomatik Category ELISA Kit Prices $809.00, $3,557.00, $6,468.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 6.5 pg/mL Range 15.62-1000 pg/mL

Junctional Adhesion Molecule 3 (JAM3), Human, ELISA Kit - DL-JAM3-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human JAM3 ELISA Kit - abx574945 from Abbexa Category ELISA Kit Sensitivity 6.2 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Human JAM-C ELISA Kit - RAB1067 from Sigma-Aldrich Category ELISA Kit Prices $390.00 Sizes 1 kt Sensitivity 0.12 ng/ml

Human Junctional adhesion molecule C(JAM3) ELISA Kit - EKC34318 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,287.50 Sizes 96 t, 5x96t, 10x96t Sensitivity 9.75 pg/ml Range 39 pg/ml-2500 pg/ml

Human JAM-C ELISA - ELH-JAMC-1 from RayBiotech Category ELISA Kit Prices $398.00, $716.40, $1,592.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human JAM3 ELISA Kit - E021216 from Biobool Category ELISA Kit Sensitivity Typically less than 6.5pg/mL.

JAM3 ELISA Kit (Human) (OKCD02053) - OKCD02053 from Aviva Systems Biology Category ELISA Kit Prices $585.00 Sizes 96 wells Sensitivity < 6.5 pg/mL Range 15.6 - 1,000 pg/mL

anti-JAM-C antibody [CRAM-18 F26] - ARG23308 from Arigo Biolaboratories Category ELISA Kit

anti-JAM-C antibody [CRAM-18 F26] (azide free) - ARG23311 from Arigo Biolaboratories Category ELISA Kit

anti-JAM-C antibody [CRAM-18 F26] (FITC) - ARG23310 from Arigo Biolaboratories Category ELISA Kit

anti-JAM-C antibody [CRAM-18 F26] (Biotin) - ARG23309 from Arigo Biolaboratories Category ELISA Kit

Junctional Adhesion Molecule 3 (JAM3), ELISA Kit - MBS450721 from MyBioSource Category ELISA Kit Prices $445.00, $590.00, $2,620.00, $5,095.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <6.2pg/mL Range 15.625-1000pg/mL

Junctional Adhesion Molecule 3 (JAM3), ELISA Kit - MBS9376769 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

JAM3 ELISA Kit (Human) (OKCA02114) - OKCA02114 from Aviva Systems Biology Category ELISA Kit Sensitivity 9.75 pg/mL Range 39 pg/mL-2,500 pg/mL

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