Gene Symbol | COMMD3 |
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Entrez Gene | 23412 |
Alt Symbol | BUP, C10orf8 |
Species | Human |
Gene Type | protein-coding |
Description | COMM domain containing 3 |
Other Description | COMM domain-containing protein 3|protein Bup |
Swissprots | Q5T8Y9 D3DRU7 Q9UBI1 |
Accessions | EAW86149 EAW86155 Q9UBI1 AF078848 AAD44480 AF201948 AAF17240 AK128789 BAG54735 AW169042 AY542159 AAS22241 BC022898 AAH22898 BF695081 BG496810 BQ930333 BX647275 NM_012071 NP_036203 |
Function | May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (PubMed:23637203). {ECO:0000269|PubMed:15799966, ECO:0000269|PubMed:23637203, ECO:0000305|PubMed:21778237}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:21778237}. Nucleus {ECO:0000269|PubMed:21778237}. |
Tissue Specificity | Widely expressed with highest expression in thymus. {ECO:0000269|PubMed:15799966}. |
Anti-COMMD3 antibody - ab67084 from Abcam
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Anti-COMMD3 / BUP Antibody - LS-C307042 from LifeSpan Bioscience
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Anti-COMMD3 / BUP Antibody - LS-C307041 from LifeSpan Bioscience
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Anti-COMMD3 / BUP Antibody (aa145-195) - LS-C290736 from LifeSpan Bioscience
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COMMD3 Antibody - NBP1-88519 from Novus Biologicals
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COMMD3 Antibody - H00023412-B01P from Novus Biologicals
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COMMD3 Antibody - H00023412-B01 from Novus Biologicals
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COMMD3 Antibody - H00023412-A01 from Novus Biologicals
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COMMD3 Antibody (2E2) - H00023412-M01 from Novus Biologicals
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COMMD3 Polyclonal Antibody - bs-8183R from Bioss
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Anti-COMMD3 antibody produced in mouse - SAB1407209 from Sigma-Aldrich
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Monoclonal Anti-COMMD3 antibody produced in mouse - SAB1403136 from Sigma-Aldrich
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Anti-COMMD3 antibody produced in rabbit - HPA036584 from Sigma-Aldrich
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Anti -COMMD3 (COMM Domain-containing Protein 3, Protein Bup, Protein PIL, C10orf8, BUP) - 125204 from USBiological Life Science
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Anti -COMMD3 (COMM Domain-containing Protein 3, Protein Bup, Protein PIL, C10orf8, BUP) - 125205 from USBiological Life Science
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Anti -COMMD3 (COMM Domain-containing Protein 3, Protein Bup, Protein PIL, C10orf8, BUP)(AP) - 125205-AP from USBiological Life Science
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Anti -COMMD3 (COMM Domain-containing Protein 3, Protein Bup, Protein PIL, C10orf8, BUP)(Biotin) - 125205-Biotin from USBiological Life Science
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Anti -COMMD3 (COMM Domain-containing Protein 3, Protein Bup, Protein PIL, C10orf8, BUP)(FITC) - 125205-FITC from USBiological Life Science
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Anti -COMMD3 (COMM Domain-containing Protein 3, Protein Bup, Protein PIL, C10orf8, BUP)(HRP) - 125205-HRP from USBiological Life Science
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Anti -COMMD3 (COMM Domain-containing Protein 3, Protein Bup, Protein PIL, C10orf8, BUP)(PE) - 125205-PE from USBiological Life Science
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COMMD3 antibody - H00023412-A01 from Acris Antibodies
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COMMD3 antibody - H00023412-B01 from Acris Antibodies
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COMMD3 antibody - H00023412-B01P from Acris Antibodies
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COMMD3 antibody - H00023412-M01 from Acris Antibodies
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BUP mAb1, Monoclonal Antibody - MBS478025 from MyBioSource
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