TEAD3

Gene Symbol	TEAD3
Entrez Gene	7005
Alt Symbol	DTEF-1, ETFR-1, TEAD-3, TEAD5, TEF-5, TEF5
Species	Human
Gene Type	protein-coding
Description	TEA domain family member 3
Other Description	TEA domain family member 5|transcriptional enhancer factor 5|transcriptional enhancer factor TEF-5|transcriptional enhancer factor TEF-5 (DTEF-1)
Swissprots	Q5BJG7 Q99594 Q8N6Y4 O95910
Accessions	EAX03835 EAX03836 EAX03837 EAX03838 Q99594 AF142482 AAD29052 AK226144 BC010053 AAH10053 BC027877 AAH27877 BC091488 AAH91488 BQ719548 DA856821 JF432847 ADZ16064 X94439 CAA64213 NM_003214 NP_003205
Function	Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer. {ECO:0000269|PubMed:18579750, ECO:0000269|PubMed:19324877}.
Subcellular Location	Nucleus.
Tissue Specificity	Preferentially expressed in the placenta.
Top Pathways	Hippo signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TEAD3 Antibody - 13224 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Polyclonal

TEF-5 (Q-14) - sc-132465 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

TEF-5 (L-17) - sc-102130 from Santa Cruz Biotechnology Prices $279.00 Sizes 50 µg/0.5 ml Host Rabbit Clonality Polyclonal

Anti-TEAD3 antibody - ab75192 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-TEAD3 antibody - ab123327 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TEAD3 antibody - ab138246 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (His246) - LS-C193255 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (aa281-330) - LS-C30262 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (aa81-110, AP) - LS-C271239 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (aa197-246) - LS-C200771 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (aa81-110, APC) - LS-C271241 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (aa143-192) - LS-C109856 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (N-Terminus) - LS-C80195 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (aa81-110, Biotin) - LS-C271242 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (aa81-110, FITC) - LS-C271243 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (C-Terminus) - LS-C30406 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (aa81-110, PE) - LS-C271245 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (aa81-110, Azide-free, HRP) - LS-C271244 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (FITC) - LS-C318259 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (HRP) - LS-C318255 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (Biotin) - LS-C318260 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (aa81-110) - LS-C325653 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody (clone 1C4) - LS-C198322 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1C4

Anti-TEAD3 Antibody (aa82-110) - LS-C161792 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-TEAD3 Antibody - LS-C318256 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

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