TEAD3

Gene Symbol TEAD3
Entrez Gene 7005
Alt Symbol DTEF-1, ETFR-1, TEAD-3, TEAD5, TEF-5, TEF5
Species Human
Gene Type protein-coding
Description TEA domain family member 3
Other Description TEA domain family member 5|transcriptional enhancer factor 5|transcriptional enhancer factor TEF-5|transcriptional enhancer factor TEF-5 (DTEF-1)
Swissprots Q5BJG7 Q99594 Q8N6Y4 O95910
Accessions EAX03835 EAX03836 EAX03837 EAX03838 Q99594 AF142482 AAD29052 AK226144 BC010053 AAH10053 BC027877 AAH27877 BC091488 AAH91488 BQ719548 DA856821 JF432847 ADZ16064 X94439 CAA64213 NM_003214 NP_003205
Function Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer. {ECO:0000269|PubMed:18579750, ECO:0000269|PubMed:19324877}.
Subcellular Location Nucleus.
Tissue Specificity Preferentially expressed in the placenta.
Top Pathways Hippo signaling pathway

TEF-5 CRISPR/Cas9 KO Plasmid (h) - sc-403417 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEF-5 HDR Plasmid (h) - sc-403417-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEF-5 Double Nickase Plasmid (h) - sc-403417-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEF-5 Double Nickase Plasmid (h2) - sc-403417-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEF-5 CRISPR Activation Plasmid (h) - sc-403417-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEF-5 CRISPR Activation Plasmid (h2) - sc-403417-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEF-5 Lentiviral Activation Particles (h) - sc-403417-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEF-5 Lentiviral Activation Particles (h2) - sc-403417-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEF-5 siRNA (h) - sc-95636 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TEF-5 shRNA Plasmid (h) - sc-95636-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TEF-5 shRNA (h) Lentiviral Particles - sc-95636-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN21197 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21197 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09327 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09327

TEAD3 siRNA (Human) - CRH4782 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TEAD3 RNAi - H00007005-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TEAD3 - MBS8237287 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TEAD3 (NM_003214.3) - SHH425448 from Creative biogene

Category siRNA
Species Reactivities Human

TEAD3 shRNA Plasmid (Human) - CHH4782 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TEAD3 miRNA 3'UTR clone - MiUTR1H-10306 from Creative biogene

Species Reactivities Human
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