TEAD3

Gene Symbol	TEAD3
Entrez Gene	7005
Alt Symbol	DTEF-1, ETFR-1, TEAD-3, TEAD5, TEF-5, TEF5
Species	Human
Gene Type	protein-coding
Description	TEA domain family member 3
Other Description	TEA domain family member 5|transcriptional enhancer factor 5|transcriptional enhancer factor TEF-5|transcriptional enhancer factor TEF-5 (DTEF-1)
Swissprots	Q5BJG7 Q99594 Q8N6Y4 O95910
Accessions	EAX03835 EAX03836 EAX03837 EAX03838 Q99594 AF142482 AAD29052 AK226144 BC010053 AAH10053 BC027877 AAH27877 BC091488 AAH91488 BQ719548 DA856821 JF432847 ADZ16064 X94439 CAA64213 NM_003214 NP_003205
Function	Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer. {ECO:0000269|PubMed:18579750, ECO:0000269|PubMed:19324877}.
Subcellular Location	Nucleus.
Tissue Specificity	Preferentially expressed in the placenta.
Top Pathways	Hippo signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TEAD3 full length protein - ab159663 from Abcam Category Protein Source Wheat germ Species Human

Human TEAD3 protein fragment - ab159664 from Abcam Category Protein Source Wheat germ Species Human

TEAD3 Antibody Blocking Peptide - LS-E3161 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TEAD3 Antibody Blocking Peptide - LS-E12042 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TEAD3 Antibody Blocking Peptide - LS-E13750 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TEAD3 Protein - H00007005-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human TEAD3 Protein - H00007005-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TEAD3-Antibody-N-term-Blocking-Peptide - BP14305a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TEAD3 Protein Lysate (APL10226) - APL10226 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

TEAD3 Protein Lysate (APL10227) - APL10227 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

Human TEAD3 protein - orb244938 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

TEAD3 / TEF5 - H00007005-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TEAD3 / TEF5 - H00007005-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TEAD3 / TEF5 - H00007005-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TEAD3 / TEF5 - H00007005-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TEAD3 fusion protein - ag3875 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

TEAD3 fusion protein - ag4407 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

TEF-5 (H246) Peptide - BS9255P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Transcriptional enhancer factor TEF-5(TEAD3) - CSB-YP860344HU CSB-BP860344HU CSB-MP860344HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human Transcriptional enhancer factor TEF-5 - CSB-EP860344HU from Cusabio Category Protein Source E.coli Species Human

TEAD3 Protein - abx164054 from Abbexa Category Protein Species Human, Mouse

TEAD3 Recombinant Protein Antigen - NBP1-83949PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TEAD3 Protein Lysate - orb333196 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

TEAD3 Peptide, Human - M34GP15771H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant human Transcriptional enhancer factor TEF-5 - AP71507 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

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