HTRA3

Gene Symbol	HTRA3
Entrez Gene	94031
Alt Symbol	Prsp, Tasp
Species	Human
Gene Type	protein-coding
Description	HtrA serine peptidase 3
Other Description	high-temperature requirement factor A3|pregnancy-related serine protease|probable serine protease HTRA3|serine protease HTRA3
Swissprots	P83110 Q7Z7A2
Accessions	EAW82345 EAW82346 P83110 AL547377 AW072765 AY040094 AAK71475 AY280665 AAP42282 AY280666 AAP42283 BC034390 AAH34390 BC035717 AAH35717 DN996853 DQ891188 ABM82114 DQ894371 ABM85297 XM_011513596 XP_011511898 NM_001297559 NP_001284488 NM_053044 NP_444272
Function	Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity). May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization. {ECO:0000250}.
Subcellular Location	Secreted {ECO:0000269|PubMed:21321049}. Note=Secretion increased during decidualization of endometrial stromal cells.
Tissue Specificity	Widely expressed, with highest levels in both adult and fetal heart, ovary, uterus placenta, and bladder. In the endometrium, expressed in epithelial glands and the stroma. Also present in leukocytes. Isoform 1 is predominant in heart and skeletal muscle, whereas isoform 2 is predominant in placenta and kidney. {ECO:0000269|PubMed:12513693, ECO:0000269|PubMed:16650464, ECO:0000269|PubMed:21321049}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human HtrA3 full length protein - ab134450 from Abcam Category Protein Prices $840.00 Sizes 50 µl Source Insect cells Species Human

Human HtrA3 protein fragment - ab164959 from Abcam Category Protein Source Wheat germ Species Human

HTRA3 Antibody Blocking Peptide - LS-E23538 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TASP / LANCL2 Antibody Blocking Peptide - LS-E20904 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TASP / LANCL2 Antibody Blocking Peptide - LS-E20905 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HtrA3 Partial Recombinant Protein - H00094031-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human HtrA3 Protein - P4932 from Novus Biologicals Category Protein Prices $949.00 Sizes 5 µg Source insect cells Species Human

HtrA3 Peptide - P0343 from Novus Biologicals Category Peptide Species Human

HtrA3 Peptide - P0342 from Novus Biologicals Category Peptide Species Human

HtrA3-Antibody-C-term-Blocking-Peptide - BP1332b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HtrA3-Antibody-N-term-Blocking-Peptide - BP1332a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HTRA3-Antibody-Center-Blocking-peptide - BP13989c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HTRA3 - H00094031-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

HTRA3 - H00094031-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

HTRA3 - P4932 from Acris Antibodies Category Protein Prices $750.00 Sizes 5 µg Species Human

HTRA3 fusion protein - ag4118 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Probable serine protease HTRA3(HTRA3) - CSB-YP010903HU CSB-EP010903HU CSB-BP010903HU CSB-MP010903HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Probable serine protease HTRA3 (HTRA3), Recombinant Protein - MBS950685 from MyBioSource Category Protein Prices $1,215.00, $1,215.00, $1,435.00, $1,435.00, $1,965.00, $1,965.00, $2,430.00, $2,430.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

HtrA3 Recombinant Protein Antigen - NBP1-87211PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

HTRA3 Peptide, Human - M34GP07356H from Creative Peptides Category Peptide Source Synthetic. Species Human

HtrA3 Recombinant Protein Antigen - NBP2-56875PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Search more