NANOS2

Gene Symbol	NANOS2
Entrez Gene	339345
Alt Symbol	NOS2
Species	Human
Gene Type	protein-coding
Description	nanos homolog 2 (Drosophila)
Other Description	NOS-2|nanos homolog 2
Swissprots	Q17R30 Q4G0P8 P60321
Accessions	P60321 BC042883 AAH42883 BC117484 AAI17485 BC117486 AAI17487 HQ258065 ADR82819 NM_001029861 NP_001025032
Function	Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for premeiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for the maintenance of the spermatogonial stem cell population. Not essential for the assembly of P-bodies but is required for the maintenance of their normal state (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:19168545}. Cytoplasm, P-body {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:19168545}. Note=Localizes at P-bodies during gonocyte development (By similarity). More abundant in perinuclear region of the cytoplasm of the germ cells of the adult testis. {ECO:0000250}.
Tissue Specificity	Testis and ovary. Expression found in several spermatogenic stages: in cells on the periphery of the tubules which could correspond to spermatogonia, in spermatocytes and in round spermatids (at protein level). {ECO:0000269|PubMed:19168545, ECO:0000269|PubMed:21421998}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NANOS2 protein fragment - ab166264 from Abcam Category Protein Source Wheat germ Species Human

NANOS2 / NOS2 Antibody Blocking Peptide - LS-E5909 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NANOS2 / NOS2 Antibody Blocking Peptide - LS-E7051 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NANOS2 / NOS2 Antibody Blocking Peptide - LS-E30517 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NANOS2 / NOS2 Antibody Blocking Peptide - LS-E30516 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NOS2 / iNOS Antibody Blocking Peptide - LS-E1207 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NOS2 / iNOS Antibody Blocking Peptide - LS-E3035 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NOS2 / iNOS Antibody Blocking Peptide - LS-E22985 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human iNOS Protein - H00004843-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Nanos2 Partial Recombinant Protein - H00339345-Q01 from Novus Biologicals Category Protein Species Human

Nanos2 Blocking Peptide - NBP1-76917PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Nanos2 Blocking Peptide - NBP1-76370PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Nanos2 Peptide - P1218 from Novus Biologicals Category Peptide Species Human

NANOS2-Antibody-Center-Blocking-Peptide - BP18474c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NANOS2-Antibody-C-term-Blocking-Peptide - BP2730b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Nanos2 Peptide - GTX85391-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

Nanos2 Peptide - GTX85392-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

Human NANOS2 protein - orb244395 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

NANOS2 - H00339345-Q01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

NANOS2 - H00339345-Q01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

NANOS2 - H00339345-Q01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

NANOS2 Control Peptide - AP30581CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

NANOS2 Control Peptide - AP30582CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Nanos2 Peptide - 4647P from ProSci Category Peptide Species Human

NOS2, Human Recombinant Protein - GWB-PS8D90 from Genway Biotech Category Protein Prices $600.00 Sizes 10 µg Species Human

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