Sox2

Gene Symbol Sox2
Entrez Gene 20674
Alt Symbol Sox-2, lcc, ysb
Species Mouse
Gene Type protein-coding
Description SRY (sex determining region Y)-box 2
Other Description SRY-box containing gene 2|transcription factor SOX-2
Swissprots P48432
Accessions CAA63847 EDL35051 P48432 AB108673 BAC75668 AB221649 AK131933 BAE20882 AK149358 BAE28833 BC057574 AAH57574 BY713734 CD353783 CD354017 U31967 AAC31791 NM_011443 NP_035573
Function Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267, ECO:0000269|PubMed:17097055}.
Tissue Specificity Expressed in the brain and retina. A very low level expression is seen in the stomach and lung. Expressed in developing urogenital ridge.
Top Pathways Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells

Anti-SOX2 (GlcNAc S248) antibody - ab136167 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SOX2 (GlcNAc S248) antibody (ab136167) at 1 µg/mlLane 1 : E14Tg2a (Mouse embryonic stem cell line) Whole Cell LysateLane 2 : IOUD2 (Mouse embryonic stem cell line) Whole Cell LysateLane 3 : E14Tg2a (Mouse embryonic stem cell line) Whole Cell Lysate with SOX2 (glcnac S248) peptide (ab157602) at 1 µg/mlLane 4 : IOUD2 (Mouse embryonic stem cell line) Whole Cell Lysate with SOX2 (glcnac S248) peptide (ab157602) at 1 µg/mlLane 5 : E14Tg2a (Mouse embryonic stem cell line) Whole Cell Lysate with Mouse SOX2 peptide (ab157771) at 1 µg/mlLane 6 : IOUD2 (Mouse embryonic stem cell line) Whole Cell Lysate with Mouse SOX2 peptide (ab157771) at 1 µg/mlLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

SOX2 Polyclonal Antibody - bs-0523R from Bioss

Prices $279.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Lane 1: mouse embryo lysates Lane 2: mouse lung lysates probed with Anti SOX2 Polyclonal Antibody, Unconjugated (bs-0523R) at 1:200 in 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90min in 37˚C. Predicted band 32kD. Observed band size: 32kD.

Monoclonal Anti-SOX2 antibody produced in mouse - SAB5300177 from Sigma-Aldrich

Prices $347.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 10F10
<B>Immunoblotting</B><BR/>Monoclonal Anti-SOX2 <B>Cat. No. SAB5300177</B>: Western blot analysis using Anti-SOX2 antibody against the following:<BR/><B>Lane</B><BR/>1. HEK293 <BR/>2. SOX2-hIgGFc transfected HEK293 cell lysate.

SOX2 Antibody (OAAD00390) - OAAD00390 from Aviva Systems Biology

Prices $335.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 10F10

Mouse-Sox2-Antibody-N-term - AP20939b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysates from NCCIT, mouse F9 cell line (from left to right), using Sox2 Antibody (N-term)(Cat. #AP20939b). AP20939b was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

Mouse-Sox2-Antibody-N-term - AP21154a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Anti-(Mouse) Sox2 Antibody (N-term) at 1:1000 dilution + NCCIT whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size :34 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

FCER2-Antibody - AO1490a from Abgent, a WuXi AppTec company

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5B5
Figure 1: Flow cytometric analysis of Raji cells using FCER2 mouse mAb (green) and negative control (purple).

SOX2 Antibody (OABF00181) - OABF00181 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SOX2 antibody - AM06557SU-N from Acris Antibodies

Prices $330.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 10F10
Immunohistochemical analysis of paraffin-embedded lung cancer tissues (left) and esophageal cancer tissues (right) using SOX2 antibody Cat.-No AM06557SU-N with DAB staining.

Sox2 antibody - STJ6014 from St John's Laboratory Ltd

Host Mouse
Clonality Monoclonal
Clone 2A10-F11-F12

Sox2 Antibody - E220095-1 from Enogene

Prices $145.00
Sizes 50μg/50μl

Sox2 Antibody - E220095-2 from Enogene

Prices $225.00
Sizes 100μg/100μl

Sox2 antibody (pAb) - 39823 from ActiveMotif

Prices $95.00, $410.00
Sizes 10 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Sox2 antibody (pAb) tested by Western blot. HeLa cell extract expressing mouse Sox2 (50 µg per lane) probed with Sox2 antibody at a dilution of 1: 5,000.

Sox2, Monoclonal Antibody - MBS851014 from MyBioSource

Prices $225.00, $290.00
Sizes 50 µg, 100 µg
Host Mouse
Clonality Monoclonal

Sox2, Monoclonal Antibody - MBS475010 from MyBioSource

Prices $335.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A10-F11-F12
Western blot detection of Sox2 antibody in F9 cell lysates using Sox2 antibody (1:1000 diluted).Predicted band size:35KDa.Observed band size:35KDa.

SOX2, Monoclonal Antibody - MBS850914 from MyBioSource

Prices $290.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 10F10

Anti-SOX2 (aa 200-300) polyclonal antibody - DPABH-28609 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

SOX 2 - 347 003 from Synaptic Systems

Host Rabbit
Clonality Polyclonal
Cat. No. 347 003 dilution: 1 : 1000 sample: newborn rat brain homogenate

SOX2 - AMB-7595 from Nordic BioSite

Host Mouse
Clonality Monoclonal
Clone 10F10
Immunofluorescence analysis of NTERA-2 cells using SOX2 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin

Sox2 Antibody - N-terminal region (OAAB18899) - OAAB18899 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Sox2 Antibody - N-terminal region (OAAB19114) - OAAB19114 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Sox2, Polyclonal Antibody - MBS9211721 from MyBioSource

Prices $155.00, $340.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal

Sox2, Polyclonal Antibody - MBS9211294 from MyBioSource

Prices $155.00, $340.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal

anti-SOX-2 antibody [SP76] - ARG53588 from Arigo Biolaboratories

ARG53588 anti-SOX-2 antibody [SP76] WB image Western Blot: MCF7 stained with SOX-2 antibody [SP76] (ARG53588)

anti-SOX-2 antibody - ARG54002 from Arigo Biolaboratories

ARG54002 anti-Sox2 antibody [2A10-F11-F12] WB image Western Blot: Sox2 in mES cell lysates stained with Sox2 antibody [2A10-F11-F12] (ARG54002) (diluted in 1: 1000). Predicted band size: 35KDa, Observed band size: 35KDa. Kindly provided by Dr. Qintong Li at the College of Life Sciences, Sichuan University.
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