Sox2

Gene Symbol Sox2
Entrez Gene 20674
Alt Symbol Sox-2, lcc, ysb
Species Mouse
Gene Type protein-coding
Description SRY (sex determining region Y)-box 2
Other Description SRY-box containing gene 2|transcription factor SOX-2
Swissprots P48432
Accessions CAA63847 EDL35051 P48432 AB108673 BAC75668 AB221649 AK131933 BAE20882 AK149358 BAE28833 BC057574 AAH57574 BY713734 CD353783 CD354017 U31967 AAC31791 NM_011443 NP_035573
Function Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267, ECO:0000269|PubMed:17097055}.
Tissue Specificity Expressed in the brain and retina. A very low level expression is seen in the stomach and lung. Expressed in developing urogenital ridge.
Top Pathways Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells

Sox-2 CRISPR/Cas9 KO Plasmid (m) - sc-423086 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Sox-2 HDR Plasmid (m) - sc-423086-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Sox-2 Double Nickase Plasmid (m) - sc-423086-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Sox-2 Double Nickase Plasmid (m2) - sc-423086-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Sox-2 CRISPR Activation Plasmid (m) - sc-423086-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Sox-2 CRISPR Activation Plasmid (m2) - sc-423086-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Sox-2 Lentiviral Activation Particles (m) - sc-423086-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Sox-2 Lentiviral Activation Particles (m2) - sc-423086-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Sox-2 siRNA (m) - sc-38409 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Sox-2 shRNA Plasmid (m) - sc-38409-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Sox-2 shRNA (m) Lentiviral Particles - sc-38409-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN41837 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND41837 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SOX2 siRNA (Mouse) - CRM3858 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

SOX2 - MBS8201826 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse SOX2 (NM_011443.3) - SHH415400 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse SOX2 siRNA - orb283334 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

SOX2 shRNA Plasmid (Mouse) - CHM3858 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

SOX2 miRNA 3'UTR clone - MiUTR1M-11100 from Creative biogene

Species Reactivities Mouse
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