ELOVL1

Gene Symbol	ELOVL1
Entrez Gene	64834
Alt Symbol	CGI-88, Ssc1
Species	Human
Gene Type	protein-coding
Description	ELOVL fatty acid elongase 1
Other Description	3-keto acyl-CoA synthase ELOVL1|ELOVL FA elongase 1|elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1|elongation of very long chain fatty acids protein 1|very-long-chain 3-oxoacyl-CoA synthase 1
Swissprots	Q5JUY3 Q9NVD9 B4DP24 Q9Y396 Q8WXU3 Q53HT2 Q9BW60
Accessions	EAX07100 Q9BW60 AA635780 AF151846 AAD34083 AF336793 AAL71993 AK001653 BAA91813 AK130174 AK222498 BAD96218 AK298163 BAG60436 AL537185 BC000618 AAH00618 BC095456 AAH95456 BM556982 BP208926 BP281965 BU180063 BU786323 BU857779 CB149715 NM_001256399 NP_001243328 NM_001256401 NP_001243330 NM_001256402 NP_001243331 NM_022821 NP_073732 NR_046117
Function	Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs. {ECO:0000269|PubMed:20166112, ECO:0000269|PubMed:20937905}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:20937905}; Multi-pass membrane protein {ECO:0000255}.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:20937905}.
Top Pathways	Fatty acid elongation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ELOVL1 ELISA Kit (Sandwich ELISA) - LS-F9396 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.062 ng/ml Range 0.156-10 ng/ml

Rat ELOVL1 ELISA Kit (Sandwich ELISA) - LS-F9378 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.054 ng/ml Range 0.156-10 ng/ml

Human ELOVL1 ELISA Kit (Sandwich ELISA) - LS-F11368 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Human ELOVL1 ELISA Kit - abx151398 from Abbexa Category ELISA Kit Sensitivity 0.062 ng/ml Range 0.156 ng/ml - 10 ng/ml

Aquaporin 9 (AQP9), Human, ELISA Kit - SEA578Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.054ng/mL Range 0.156-10ng/mL

Elongation Of Very Long Chain Fatty Acids Like Protein 1 (ELOVL1), Human, ELISA Kit - SEJ169Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.056ng/mL Range 0.156-10ng/mL

Elongation of very long chain fatty acids protein 1, ELOVL1, Human, ELISA Kit - E13834h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

ELISA Kit for Elongation Of Very Long Chain Fatty Acids Like Protein 1 (ELOVL1) - SEJ169Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.062ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Elongation Of Very Long Chain Fatty Acids Like Protein 1 (ELOVL1) - SEJ169Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Elongation Of Very Long Chain Fatty Acids Like Protein 1 (ELOVL1) - SEJ169Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.062ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Aquaporin 9 (AQP9) - SEA578Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 6.5pg/mL. Range 15.625-1000pg/mL The standard curve concentrations used for the ELISA's were 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL, 15.625pg/mL

Mouse ELOVL1 ELISA Kit (Custom ELISA) - LS-F17066 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Aquaporin 9 (AQP9), Human, ELISA Kit - DL-AQP9-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Elongation Of Very Long Chain Fatty Acids Like Protein 1 (ELOVL1), Human, ELISA Kit - DL-ELOVL1-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human ELOVL1 ELISA Kit - abx571803 from Abbexa Category ELISA Kit Sensitivity 0.056 ng/ml Range 0.156 ng/ml - 10 ng/ml

ELOVL1 - EKH3082 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

ELOVL1 ELISA Kit (Human) (OKEH02320) - OKEH02320 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 0.1 ng/mL Range 0.156 - 10 ng/mL

Human ELOVL1 ELISA Kit - E012950 from Biobool Category ELISA Kit Sensitivity Typically less than 0.062ng/mL.

Human Elongation of very long chain fatty acids protein 1 ELISA Kit - EK3298 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Sensitivity less than 0.1ng/ml Range 0.156-10 ng/mL

Elongation Of Very Long Chain Fatty Acids Like Protein 1 (ELOVL1), ELISA Kit - MBS454818 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.056ng/mL Range 0.156-10ng/mL

Elongation of very long chain fatty acids protein 1, ELISA Kit - MBS2887567 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.156-10 ng/mL

Elongation of very long chain fatty acids protein 1, ELISA Kit - MBS765345 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/ml Range 0.156-10ng/ml

Elongation of very long chain fatty acids protein 1, ELISA Kit - MBS9427132 from MyBioSource Category ELISA Kit Prices $555.00 Sizes 96 tests Sensitivity Less than 0.1ng/mL Range 0.156-10 ng/mL

Human ELOVL1 ELISA Kit (Sandwich ELISA) - LS-F35877 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.094 Range 0.156-10 ng/ml

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