WISP1

Gene Symbol	WISP1
Entrez Gene	8840
Alt Symbol	CCN4, WISP1c, WISP1i, WISP1tc
Species	Human
Gene Type	protein-coding
Description	WNT1 inducible signaling pathway protein 1
Other Description	CCN family member 4|CTC-458A3.8|WNT1 induced secreted protein 1|WNT1-inducible-signaling pathway protein 1|Wnt-1 inducible signaling pathway protein 1
Swissprots	Q5JBS8 Q9HCS3 Q5JBS6 O95388 E7EMM5 Q5JBS7 A8KAG6
Accessions	AAF35350 EAW92162 EAW92163 O95388 AB034725 BAB17849 AF100779 AAC96321 AI347990 AK027294 AK293031 BAF85720 AK301508 BAG63017 AK315822 BAF98713 AW291472 AY196486 AAP43924 AY196487 AAP43925 AY196488 AAP43926 BC074840 AAH74840 BC074841 AAH74841 BX476382 DN997366 EF025923 ABK13678 HG501717 KC344835 XM_006716680 XP_006716743 XM_011517358 XP_011515660 XM_011517359 XP_011515661 NM_001204869 NP_001191798 NM_001204870 NP_001191799 NM_003882 NP_003873 NM_080838 NP_543028 NR_037944
Function	Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan. {ECO:0000269|PubMed:10716946, ECO:0000269|PubMed:11782444}.
Subcellular Location	Secreted.
Tissue Specificity	Expressed in heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. Isoform 2 is expressed predominantly in scirrhous gastric carcinoma and, weakly in placenta. Overexpression is associated with several cancers including breast cancer and colon tumors. Isoform 2 is overexpressed in scirrhous gastric carcinoma.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

WISP1 293T Cell Transient Overexpression Lysate(Denatured) - H00008840-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

WISP1 overexpression lysate - LY403320 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

WISP1 overexpression lysate - LY418374 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

WISP1 293 Cell Lysate - 402881 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

WISP1 293 Cell Lysate - 408564 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

WISP-1/CCN4 Overexpression Lysate (Denatured) - H00008840-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

WISP-1/CCN4 Overexpression Lysate (Native) - NBL1-17856 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

WISP-1/CCN4 Overexpression Lysate (Native) - NBL1-17857 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

WISP1 Over-expression Lysate Product - GWB-AFA184 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

WISP1 Over-expression Lysate Product - GWB-5D7953 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human CCN4 / WISP1 HEK293 Cell Lysate (WB positive control) - 10442-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human WISP1 Human Cells Transfected Lysate (positive control) (denatured) - orb173037 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Panoply™ Human WISP1 Knockdown Stable Cell Line - CSC-DC017502 from Creative biogene Category Cell Line Species Human

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