WISP1

Gene Symbol	WISP1
Entrez Gene	8840
Alt Symbol	CCN4, WISP1c, WISP1i, WISP1tc
Species	Human
Gene Type	protein-coding
Description	WNT1 inducible signaling pathway protein 1
Other Description	CCN family member 4|CTC-458A3.8|WNT1 induced secreted protein 1|WNT1-inducible-signaling pathway protein 1|Wnt-1 inducible signaling pathway protein 1
Swissprots	Q5JBS8 Q9HCS3 Q5JBS6 O95388 E7EMM5 Q5JBS7 A8KAG6
Accessions	AAF35350 EAW92162 EAW92163 O95388 AB034725 BAB17849 AF100779 AAC96321 AI347990 AK027294 AK293031 BAF85720 AK301508 BAG63017 AK315822 BAF98713 AW291472 AY196486 AAP43924 AY196487 AAP43925 AY196488 AAP43926 BC074840 AAH74840 BC074841 AAH74841 BX476382 DN997366 EF025923 ABK13678 HG501717 KC344835 XM_006716680 XP_006716743 XM_011517358 XP_011515660 XM_011517359 XP_011515661 NM_001204869 NP_001191798 NM_001204870 NP_001191799 NM_003882 NP_003873 NM_080838 NP_543028 NR_037944
Function	Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan. {ECO:0000269|PubMed:10716946, ECO:0000269|PubMed:11782444}.
Subcellular Location	Secreted.
Tissue Specificity	Expressed in heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. Isoform 2 is expressed predominantly in scirrhous gastric carcinoma and, weakly in placenta. Overexpression is associated with several cancers including breast cancer and colon tumors. Isoform 2 is overexpressed in scirrhous gastric carcinoma.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human WISP1 full length protein - ab50041 from Abcam Category Protein Prices $110.00, $239.00 Sizes 5 µg, 20 µg Source E. coli Species Human

Human WISP1 peptide - ab24414 from Abcam Category Peptide

CCN4 / WISP1 Antibody Blocking Peptide - LS-E8153 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CCN4 / WISP1 Antibody Blocking Peptide - LS-E23295 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CCN4 / WISP1 Antibody Blocking Peptide - LS-E26525 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Human WISP-1/CCN4 Protein - NBP2-36591 from Novus Biologicals Category Protein Prices $75.00 Sizes 5 µg Species Human

Recombinant Human WISP-1/CCN4 Protein - NBP2-36503 from Novus Biologicals Category Protein Prices $69.00, $169.00 Sizes 5 µg, 20 µg Source Mouse myeloma cell line, NS0-derived Species Human

Recombinant Human WISP-1/CCN4 Protein - H00008840-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

WISP-1/CCN4 Peptide - P1860 from Novus Biologicals Category Peptide Species Human

WISP1-Antibody-Center-Blocking-Peptide - BP6255a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

WISP1 Recombinant Protein (Active) - GTX48099-PRO from GeneTex Category Protein Prices $299.00 Sizes 20 μg Source E. coli Species Human

WISP1 blocking peptide - GTX88924-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat

Recombinant Human WISP-1/CCN4, CF - 1627-WS-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Thr23-Asn367, with a 10-His tag

Human CCN 4 protein - orb83153 from Biorbyt Category Protein Prices $162.00, $323.00, $612.00 Sizes 5 μg, 20 μg, 100 μg Source Human Species Human

WISP1 protein - 30R-AW001 from Fitzgerald Category Protein Prices $235.00 Sizes 20 µg Source E.coli

Human WISP1 Protein - abx069707 from Abbexa Category Protein Source E.coli Species Human

WISP1 Peptide - AC21-1361-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

WISP1 - PA526 from Acris Antibodies Category Protein Prices $135.00 Sizes 5 µg Source E. coli Species Human

WISP1 - PA526X from Acris Antibodies Category Protein Prices $235.00 Sizes 20 µg Source E. coli Species Human

WISP1 - H00008840-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

WISP1 - H00008840-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

WISP1 - P6056 from Acris Antibodies Category Protein Prices $370.00 Sizes 20 µg Species Human

WISP-1, Recombinant Human - 213-10470-1 from RayBiotech Category Protein Prices $75.00 Sizes 1 µg Source Escherichia coli (E.coli) Species Human

Recombinant Human WISP-1 - 213-10470-2 from RayBiotech Category Protein Prices $190.00 Sizes 2 µg Source Escherichia coli (E.coli) Species Human

WNT1 Inducible Signaling Pathway Protein 1 (WISP1), Human - 20-9197 from ARP American Research Products Category Protein Prices $521.00 Sizes 50 µg Source E.coli Species Human

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