SPRY4

Gene Symbol	SPRY4
Entrez Gene	81848
Alt Symbol	HH17
Species	Human
Gene Type	protein-coding
Description	sprouty homolog 4 (Drosophila)
Other Description	protein sprouty homolog 4
Swissprots	A4FVB2 Q9C004 A4FVB3 Q6QIX2 Q9C003
Accessions	AAS46253 Q9C004 AF227516 AAK00652 AF251060 AAK34950 AK096464 BAC04798 AK226147 BC125095 AAI25096 BC125096 AAI25097 BP387943 DA183391 T32786 XM_005268519 XP_005268576 XM_011537685 XP_011535987 NM_001127496 NP_001120968 NM_001293289 NP_001280218 NM_001293290 NP_001280219 NM_030964 NP_112226
Function	Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1. {ECO:0000269|PubMed:12717443}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:12027893}. Cell projection, ruffle membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Top Pathways	Jak-STAT signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Sprouty 4 full length protein - ab171684 from Abcam Category Protein Source E. coli Species Human

Human Sprouty 4 protein fragment - ab153536 from Abcam Category Protein Source Wheat germ Species Human

Sprouty 4 / SPRY4 Antibody Blocking Peptide - LS-E18305 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Sprouty 4 / SPRY4 Antibody Blocking Peptide - LS-E8961 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Sprouty 4 / SPRY4 Antibody Blocking Peptide - LS-E8960 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Sprouty 4 / SPRY4 Antibody Blocking Peptide - LS-E7429 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPRY4 Partial Recombinant Protein - H00081848-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human SPRY4 Protein - NBP2-22822 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

Phospho-SPRY4Y75-Antibody-Blocking-peptide - BP3585a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

SPRY4-Y75-Antibody-Blocking-Peptide - BP7446d from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SPRY4-Antibody-C-term-Blocking-peptide - BP7446b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SPRY4 protein (His tag) - 80R-3032 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

Sprouty homolog 4 / SPRY4 (1-299, His-tag) - AR51150PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Sprouty homolog 4 / SPRY4 (1-299, His-tag) - AR51150PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Sprouty homolog 4 / SPRY4 - H00081848-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Sprouty homolog 4 / SPRY4 - H00081848-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SPRY4, 1-299aa, Human, His tag, E.coli - 01-P2326 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

SPRY4 fusion protein - Ag18861 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

SPRY4 fusion protein - Ag18574 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

SPRY4, 1-299aa, Human, His tag, E.coli - GWB-ATG509 from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Species Human

Recombinant Human CD7, His-tagged - SPRY4-2326H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human SPRY4, His-tagged - SPRY4-2939H from Creative Biomart Category Protein Source E.coli Species Human

Sprouty homolog 4 (Spry-4) peptide - pep0230 from Covalab Category Peptide Species Human, Mouse

Recombinant Human Protein sprouty homolog 4(SPRY4) - CSB-YP866335HU CSB-EP866335HU CSB-BP866335HU CSB-MP866335HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SPRY4, 1-299aa, Human, His tag, E.coli (Denatured) - ATGP2326 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

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