SPRY4

Gene Symbol SPRY4
Entrez Gene 81848
Alt Symbol HH17
Species Human
Gene Type protein-coding
Description sprouty homolog 4 (Drosophila)
Other Description protein sprouty homolog 4
Swissprots A4FVB2 Q9C004 A4FVB3 Q6QIX2 Q9C003
Accessions AAS46253 Q9C004 AF227516 AAK00652 AF251060 AAK34950 AK096464 BAC04798 AK226147 BC125095 AAI25096 BC125096 AAI25097 BP387943 DA183391 T32786 XM_005268519 XP_005268576 XM_011537685 XP_011535987 NM_001127496 NP_001120968 NM_001293289 NP_001280218 NM_001293290 NP_001280219 NM_030964 NP_112226
Function Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1. {ECO:0000269|PubMed:12717443}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12027893}. Cell projection, ruffle membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Top Pathways Jak-STAT signaling pathway

Sprouty 4 CRISPR/Cas9 KO Plasmid (h) - sc-402081 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sprouty 4 HDR Plasmid (h) - sc-402081-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sprouty 4 Double Nickase Plasmid (h) - sc-402081-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sprouty 4 Double Nickase Plasmid (h2) - sc-402081-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sprouty 4 CRISPR Activation Plasmid (h) - sc-402081-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sprouty 4 CRISPR Activation Plasmid (h2) - sc-402081-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sprouty 4 Lentiviral Activation Particles (h) - sc-402081-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sprouty 4 Lentiviral Activation Particles (h2) - sc-402081-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sprouty 4 siRNA (h) - sc-41041 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sprouty 4 shRNA Plasmid (h) - sc-41041-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sprouty 4 shRNA (h) Lentiviral Particles - sc-41041-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU097061 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20532 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20532 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SPRY4 siRNA (Human) - CRJ3063 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SPRY4 - MBS8205847 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SPRY4 shRNA Plasmid (Human) - CHJ3063 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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