PVRL1

Gene Symbol PVRL1
Entrez Gene 5818
Alt Symbol CD111, CLPED1, ED4, HIgR, HV1S, HVEC, OFC7, PRR, PRR1, PVRR, PVRR1, SK-12, nectin-1
Species Human
Gene Type protein-coding
Description poliovirus receptor-related 1 (herpesvirus entry mediator C)
Other Description ectodermal dysplasia 4 (Margarita Island type)|herpes simplex virus type 1 sensitivity|herpes virus entry mediator C|herpesvirus Ig-like receptor|nectin 1|nectin-1|poliovirus receptor-like 1|poliovirus receptor-related protein 1
Swissprots O75465 Q15223 Q9HBW2 Q9HBE6 Q2M3D3
Accessions AAG16648 AAG16649 AAL47715 AAL47716 AAR88250 AAR88251 AAR88252 EAW67492 EAW67493 EAW67494 Q15223 AF060231 AAC23798 AF110314 AAD04944 AI819997 AK056455 AK091231 AK095375 AY029539 AAK33124 BC007379 BC021976 BC044230 BC064140 BC086309 BC104948 AAI04949 BC113471 AAI13472 BQ188335 HQ258297 ADR83051 X76400 CAA53980 NM_002855 NP_002846 NM_203285 NP_976030 NM_203286 NP_976031 NM_032767
Function Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between PVRL1/nectin-1 and PVRL3/nectin-3 and between PVRL1/nectin-1 and PVRL4/nectin-4. Functions as an entry receptor for herpes simplex virus and pseudorabies virus. Has some neurite outgrowth-promoting activity. {ECO:0000269|PubMed:21980294, ECO:0000269|PubMed:7721102}.
Subcellular Location Isoform Gamma: Secreted.
Top Pathways Adherens junction, Cell adhesion molecules (CAMs), Herpes simplex infection

Nectin 1 (F-10) - sc-271063 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nectin 1 (F-10): sc-271063. Western blot analysis of Nectin 1 expression in human brain tissue extract.

Nectin 1 (CK6) - sc-21722 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nectin 1 (CK6) PE: sc-21722 PE. FCM analysis of Jurkat cells. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2866.

Nectin 1 (C-20) - sc-14798 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Nectin 1 (H-62) - sc-28639 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Nectin 1 (H-62): sc-28639. Western blot analysis of Nectin 1 expression in IMR-32 whole cell lysate (A) and human brain (B), mouse brain (C) and rat brain (D) tissue extracts.

Nectin 1 (R1.302.12) - sc-69718 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nectin 1 (R1.302.12) PE: sc-69718 PE. FCM analysis of Jurkat cells. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2866.

Anti-PVRL1 antibody - ab66985 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PVRL1 antibody (ab66985) at 1 µg/mlLane 1 : Brain (Mouse) Tissue LysateLane 2 : Mouse Dorsal Root GanglionLane 3 : NIH 3T3 (Mouse embryonic fibroblast cell line) Whole Cell LysateLane 4 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466)Lysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-PVRL1 antibody - ab183114 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-PVRL1 antibody (ab183114) at 1/400 dilutionLane 1 : Human cervical cancer tissue lysateLane 2 : Human leg fibrous cystiocytoma tissue lysateLane 3 : Human fetal brain tissue lysateLysates/proteins at 30 µg per lane.SecondaryDonkey Anti-rabbit HRP at 1/5000 dilution

Anti-PVRL1 antibody - ab194572 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-FGFR1 alpha (phospho Y766) antibody (ab194527) at 1/500 dilution + A431 cell lysate at 50 µg

Anti-PVRL1 antibody - C-terminal - ab71512 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab71512 at 1/50 dilution, staining PVRL1 in human breast carcinoma by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and AEC staining.

Anti-Nectin-1 / PVRL1 Antibody (aa459-472) - LS-C3221 from LifeSpan Bioscience

Prices $285.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Nectin-1 / PVRL1 Antibody - LS-C37574 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-Nectin-1 / PVRL1 Antibody (clone 11D40, APC) - LS-C183984 from LifeSpan Bioscience

Prices $590.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
Clone 11D40

Anti-Nectin-1 / PVRL1 Antibody (aa137-186) - LS-C145254 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PVRL1 antibody LS-C145254 Western blot of MCF7 Cell lysate. Antibody concentration 1 ug/ml.

Anti-Nectin-1 / PVRL1 Antibody - LS-C192886 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of HepG2 cell lines, using PVRL1 antibody.

Anti-Nectin-1 / PVRL1 Antibody - LS-C331840 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using PVRL1 antibody.

Anti-Nectin-1 / PVRL1 Antibody (clone 6E11) - LS-C173284 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6E11
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PVRL1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PVRL1.

Anti-Nectin-1 / PVRL1 Antibody (clone 6D12) - LS-C173290 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6D12
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PVRL1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PVRL1.

Anti-Nectin-1 / PVRL1 Antibody (clone 1B6) - LS-C173268 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B6
IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-PVRL1 mouse monoclonal antibody.

Anti-Nectin-1 / PVRL1 Antibody (clone 6F8) - LS-C173291 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6F8
IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-PVRL1 mouse monoclonal antibody.

Nectin-1/PVRL1 Antibody (6F8) - NBP2-01198 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6F8
Western Blot: PVRL1 Antibody (6F8) [NBP2-01198] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PVRL1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PVRL1.

Nectin-1/PVRL1 Antibody - AF2880 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal

Nectin-1/PVRL1 Antibody - NBP1-86554 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PVRL1 Antibody [NBP1-86554] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp

Nectin-1/PVRL1 Antibody (610835) - MAB2880 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 610835
U937 human histiocytic lymphoma cell line was stained with Human Nectin‑1 Monoclonal Antibody (Catalog # MAB2880, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab')2 Secondary Antibody (Catalog # F0101B).

Nectin-1/PVRL1 Antibody - H00005818-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Nectin-1/PVRL1 Antibody [H00005818-B01P] - Analysis of PVRL1 expression in A-431.

Nectin-1/PVRL1 Antibody - H00005818-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: PVRL1 Antibody [H00005818-A01] - PVRL1 polyclonal antibody (A01), Lot # 050913JC01 Western Blot analysis of PVRL1 expression in A-431 ( Cat # L015V1 ).
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