PVRL1

Gene Symbol	PVRL1
Entrez Gene	5818
Alt Symbol	CD111, CLPED1, ED4, HIgR, HV1S, HVEC, OFC7, PRR, PRR1, PVRR, PVRR1, SK-12, nectin-1
Species	Human
Gene Type	protein-coding
Description	poliovirus receptor-related 1 (herpesvirus entry mediator C)
Other Description	ectodermal dysplasia 4 (Margarita Island type)|herpes simplex virus type 1 sensitivity|herpes virus entry mediator C|herpesvirus Ig-like receptor|nectin 1|nectin-1|poliovirus receptor-like 1|poliovirus receptor-related protein 1
Swissprots	O75465 Q15223 Q9HBW2 Q9HBE6 Q2M3D3
Accessions	AAG16648 AAG16649 AAL47715 AAL47716 AAR88250 AAR88251 AAR88252 EAW67492 EAW67493 EAW67494 Q15223 AF060231 AAC23798 AF110314 AAD04944 AI819997 AK056455 AK091231 AK095375 AY029539 AAK33124 BC007379 BC021976 BC044230 BC064140 BC086309 BC104948 AAI04949 BC113471 AAI13472 BQ188335 HQ258297 ADR83051 X76400 CAA53980 NM_002855 NP_002846 NM_203285 NP_976030 NM_203286 NP_976031 NM_032767
Function	Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between PVRL1/nectin-1 and PVRL3/nectin-3 and between PVRL1/nectin-1 and PVRL4/nectin-4. Functions as an entry receptor for herpes simplex virus and pseudorabies virus. Has some neurite outgrowth-promoting activity. {ECO:0000269|PubMed:21980294, ECO:0000269|PubMed:7721102}.
Subcellular Location	Isoform Gamma: Secreted.
Top Pathways	Adherens junction, Cell adhesion molecules (CAMs), Herpes simplex infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PVRL1 293T Cell Transient Overexpression Lysate(Denatured) - H00005818-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

PVRL1 overexpression lysate - LY404370 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PVRL1 overexpression lysate - LY419083 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PVRL1 overexpression lysate - LY430907 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PVRL1 293 Cell Lysate - 408920 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Nectin-1/PVRL1 Overexpression Lysate (Native) - NBL1-15005 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PVRL1 Over-expression Lysate Product - GWB-2601FC from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human PVRL1 / HVEC / CD111 / Nectin-1 HEK293 Cell Lysate (WB positive control) - 11611-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human PVRL1 / HVEC / CD111 / Nectin-1 HEK293 Cell Lysate (WB positive control) - 11611-H02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Nectin-1/PVRL1 Overexpression Lysate (Denatured) - H00005818-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Nectin-1/PVRL1 Overexpression Lysate (Denatured) - H00005818-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Human PVRL1 Human Cells Transfected Lysate (positive control) (denatured) - orb179336 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Human PVRL1 Human Cells Transfected Lysate (positive control) (denatured) - orb179337 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human PVRL1 Knockdown Stable Cell Line - CSC-DC012758 from Creative biogene Category Cell Line Species Human

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